KAT6B overexpression in mice causes aggression, anxiety, and epilepsy.

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Title: KAT6B overexpression in mice causes aggression, anxiety, and epilepsy.
Authors: Bergamasco MI; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Ozturk E; Department of Medicine (Royal Melbourne Hospital), Melbourne Brain Centre, University of Melbourne, Parkville VIC 3052, Australia.; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.; Department of Neurology, Alfred Hospital, Melbourne, Melbourne, VIC 3004, Australia., Casillas-Espinosa PM; Department of Medicine (Royal Melbourne Hospital), Melbourne Brain Centre, University of Melbourne, Parkville VIC 3052, Australia.; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.; Department of Neurology, Alfred Hospital, Melbourne, Melbourne, VIC 3004, Australia., Garnham AL; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Abeysekera W; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Wimmer VC; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Rajasekhar P; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Vanyai HK; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Whitehead L; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Blewitt ME; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Rogers K; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Vogel AP; Centre for Neurosciences of Speech, The University of Melbourne, Melbourne, VIC 3052, Australia.; Redenlab Inc, Melbourne, VIC 3000, Australia., Hannan AJ; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC 3010, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC 3010, Australia., Smyth GK; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; School of Mathematics and Statistics, University of Melbourne, Parkville, VIC 3010, Australia., Jones NC; Department of Medicine (Royal Melbourne Hospital), Melbourne Brain Centre, University of Melbourne, Parkville VIC 3052, Australia.; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.; Department of Neurology, Alfred Hospital, Melbourne, Melbourne, VIC 3004, Australia., Thomas T; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia., Voss AK; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.
Source: IScience [iScience] 2025 Feb 11; Vol. 28 (3), pp. 111953. Date of Electronic Publication: 2025 Feb 11 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Bergamasco+MI%22">Bergamasco MI</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Ozturk+E%22">Ozturk E</searchLink>; Department of Medicine (Royal Melbourne Hospital), Melbourne Brain Centre, University of Melbourne, Parkville VIC 3052, Australia.; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.; Department of Neurology, Alfred Hospital, Melbourne, Melbourne, VIC 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Casillas-Espinosa+PM%22">Casillas-Espinosa PM</searchLink>; Department of Medicine (Royal Melbourne Hospital), Melbourne Brain Centre, University of Melbourne, Parkville VIC 3052, Australia.; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.; Department of Neurology, Alfred Hospital, Melbourne, Melbourne, VIC 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Garnham+AL%22">Garnham AL</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Abeysekera+W%22">Abeysekera W</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Wimmer+VC%22">Wimmer VC</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Rajasekhar+P%22">Rajasekhar P</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Vanyai+HK%22">Vanyai HK</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Whitehead+L%22">Whitehead L</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Blewitt+ME%22">Blewitt ME</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Rogers+K%22">Rogers K</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Vogel+AP%22">Vogel AP</searchLink>; Centre for Neurosciences of Speech, The University of Melbourne, Melbourne, VIC 3052, Australia.; Redenlab Inc, Melbourne, VIC 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Hannan+AJ%22">Hannan AJ</searchLink>; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC 3010, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Smyth+GK%22">Smyth GK</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; School of Mathematics and Statistics, University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Jones+NC%22">Jones NC</searchLink>; Department of Medicine (Royal Melbourne Hospital), Melbourne Brain Centre, University of Melbourne, Parkville VIC 3052, Australia.; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.; Department of Neurology, Alfred Hospital, Melbourne, Melbourne, VIC 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Thomas+T%22">Thomas T</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Voss+AK%22">Voss AK</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3052, Australia.
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