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TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma.

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Title: TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma.
Authors: Wang HJ; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Shanghai Key Laboratory of Complex Prescription and MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Dong LF; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Ding LL; Shanghai Key Laboratory of Complex Prescription and MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Miao XY; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Zhang YW; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Zhao LP; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Yu LH; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Guan ZR; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Jiang YP; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Tang XQ; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Yan YX; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China., Lou JS; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Source: Theranostics [Theranostics] 2025 Feb 10; Vol. 15 (7), pp. 2991-3012. Date of Electronic Publication: 2025 Feb 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
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  Data: TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Wang+HJ%22">Wang HJ</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Shanghai Key Laboratory of Complex Prescription and MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Dong+LF%22">Dong LF</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Ding+LL%22">Ding LL</searchLink>; Shanghai Key Laboratory of Complex Prescription and MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Miao+XY%22">Miao XY</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YW%22">Zhang YW</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Zhao+LP%22">Zhao LP</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Yu+LH%22">Yu LH</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Guan+ZR%22">Guan ZR</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Jiang+YP%22">Jiang YP</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Tang+XQ%22">Tang XQ</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Yan+YX%22">Yan YX</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.<br /><searchLink fieldCode="AU" term="%22Lou+JS%22">Lou JS</searchLink>; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
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  Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2025 Feb 10; Vol. 15 (7), pp. 2991-3012. <i>Date of Electronic Publication: </i>2025 Feb 10 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101552395 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1838-7640 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218387640%22">18387640 </searchLink><i>NLM ISO Abbreviation: </i>Theranostics <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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        Value: 10.7150/thno.106469
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      – Code: eng
        Text: English
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      – TitleFull: TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma.
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              Text: 2025 Feb 10
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