Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells.

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Title: Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells.
Authors: Parikh C; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA., Glenn RA; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA., Shi Y; Department of Computational Biology, Cornell University, Ithaca, NY 14853, USA., Chatterjee K; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Kasliwal K; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Swanzey EE; The Jackson Laboratory, Bar Harbor, ME 04609, USA., Singer S; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Do SC; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Zhan Y; Mouse Genetics Core Facility, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Furuta Y; Mouse Genetics Core Facility, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Tahiliani M; Department of Biology, New York University, New York, NY 10003, USA., Apostolou E; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Polyzos A; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Koche R; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Mezey JG; Department of Computational Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address: jgm45@cornell.edu., Vierbuchen T; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: vierbuct@mskcc.org., Stadtfeld M; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: mas4011@med.cornell.edu.
Source: Stem cell reports [Stem Cell Reports] 2025 Apr 08; Vol. 20 (4), pp. 102450. Date of Electronic Publication: 2025 Mar 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE
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  Data: Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells.
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  Data: <searchLink fieldCode="AU" term="%22Parikh+C%22">Parikh C</searchLink>; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.<br /><searchLink fieldCode="AU" term="%22Glenn+RA%22">Glenn RA</searchLink>; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Department of Computational Biology, Cornell University, Ithaca, NY 14853, USA.<br /><searchLink fieldCode="AU" term="%22Chatterjee+K%22">Chatterjee K</searchLink>; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Kasliwal+K%22">Kasliwal K</searchLink>; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Swanzey+EE%22">Swanzey EE</searchLink>; The Jackson Laboratory, Bar Harbor, ME 04609, USA.<br /><searchLink fieldCode="AU" term="%22Singer+S%22">Singer S</searchLink>; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Do+SC%22">Do SC</searchLink>; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Zhan+Y%22">Zhan Y</searchLink>; Mouse Genetics Core Facility, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Furuta+Y%22">Furuta Y</searchLink>; Mouse Genetics Core Facility, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Tahiliani+M%22">Tahiliani M</searchLink>; Department of Biology, New York University, New York, NY 10003, USA.<br /><searchLink fieldCode="AU" term="%22Apostolou+E%22">Apostolou E</searchLink>; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Polyzos+A%22">Polyzos A</searchLink>; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Koche+R%22">Koche R</searchLink>; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Mezey+JG%22">Mezey JG</searchLink>; Department of Computational Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address: jgm45@cornell.edu.<br /><searchLink fieldCode="AU" term="%22Vierbuchen+T%22">Vierbuchen T</searchLink>; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Center for Stem Cell Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: vierbuct@mskcc.org.<br /><searchLink fieldCode="AU" term="%22Stadtfeld+M%22">Stadtfeld M</searchLink>; Sanford I. Weill Department of Medicine, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: mas4011@med.cornell.edu.
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