Single-cell multiomic comparison of mouse and rat spermatogenesis reveals gene regulatory networks conserved for over 20 million years.

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Title: Single-cell multiomic comparison of mouse and rat spermatogenesis reveals gene regulatory networks conserved for over 20 million years.
Authors: Whelan EC; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA. Electronic address: ewhelan@vet.upenn.edu., Swain JJ; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA., Sussman JH; Children's Hospital of Philadelphia, Philadelphia, PA, USA; Medical Scientist Training Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Graduate Group in Genomics and Computational Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Smith D; Children's Hospital of Philadelphia, Philadelphia, PA, USA., Yang F; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA., Rotolo A; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA., Avarbock MR; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA., Malekshahi C; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA., Radaelli E; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA., Beiting DP; Department of Pathobiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA., Brinster RL; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA. Electronic address: brinster@vet.upenn.edu.
Source: Stem cell reports [Stem Cell Reports] 2025 Apr 08; Vol. 20 (4), pp. 102449. Date of Electronic Publication: 2025 Mar 13.
Publication Type: Journal Article; Comparative Study; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2213-6711
DOI:10.1016/j.stemcr.2025.102449