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Functional genomics in age-related macular degeneration: From genetic associations to understanding disease mechanisms.

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Title: Functional genomics in age-related macular degeneration: From genetic associations to understanding disease mechanisms.
Authors: Ratnapriya R; Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA., Grassman F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Institute for Clinical Research and Systems Medicine, Health and Medical University, Potsdam, Germany., Chen R; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Hewitt A; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia., Du J; Department of Ophthalmology and Visual Sciences, Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, USA., Saban DR; Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USA; Department of Integrative Immunobiology, Duke University, Durham, NC, USA., Klaver CCW; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands; Institute of Molecular and Clinical Ophthalmology, University of Basel, Basel, Switzerland., Ash J; Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA., Stambolian D; Univeristy of Pennsylvania, USA., Tumminia SJ; National Eye Institute, Bethesda, MD, USA., Qian J; Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Husain D; Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA., Iyengar SK; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA., den Hollander AI; Genomics Research Center, AbbVie, North Chicago, IL, USA; Genomics Research Center, AbbVie, Cambridge, MA, USA. Electronic address: anneke.denhollander@abbvie.com.
Source: Experimental eye research [Exp Eye Res] 2025 May; Vol. 254, pp. 110344. Date of Electronic Publication: 2025 Mar 13.
Publication Type: Journal Article; Review
Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 0370707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0007 (Electronic) Linking ISSN: 00144835 NLM ISO Abbreviation: Exp Eye Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ratnapriya+R%22">Ratnapriya R</searchLink>; Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Grassman+F%22">Grassman F</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Institute for Clinical Research and Systems Medicine, Health and Medical University, Potsdam, Germany.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hewitt+A%22">Hewitt A</searchLink>; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.<br /><searchLink fieldCode="AU" term="%22Du+J%22">Du J</searchLink>; Department of Ophthalmology and Visual Sciences, Department of Biochemistry and Molecular Medicine, West Virginia University, Morgantown, USA.<br /><searchLink fieldCode="AU" term="%22Saban+DR%22">Saban DR</searchLink>; Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USA; Department of Integrative Immunobiology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Klaver+CCW%22">Klaver CCW</searchLink>; Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands; Institute of Molecular and Clinical Ophthalmology, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ash+J%22">Ash J</searchLink>; Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Stambolian+D%22">Stambolian D</searchLink>; Univeristy of Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Tumminia+SJ%22">Tumminia SJ</searchLink>; National Eye Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Qian+J%22">Qian J</searchLink>; Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Husain+D%22">Husain D</searchLink>; Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Iyengar+SK%22">Iyengar SK</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22den+Hollander+AI%22">den Hollander AI</searchLink>; Genomics Research Center, AbbVie, North Chicago, IL, USA; Genomics Research Center, AbbVie, Cambridge, MA, USA. Electronic address: anneke.denhollander@abbvie.com.
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  Data: <searchLink fieldCode="JN" term="%220370707%22">Experimental eye research</searchLink> [Exp Eye Res] 2025 May; Vol. 254, pp. 110344. <i>Date of Electronic Publication: </i>2025 Mar 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370707 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-0007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200144835%22">00144835 </searchLink><i>NLM ISO Abbreviation: </i>Exp Eye Res <i>Subsets: </i>MEDLINE
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