Parvalbumin interneurons regulate rehabilitation-induced functional recovery after stroke and identify a rehabilitation drug.

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Title: Parvalbumin interneurons regulate rehabilitation-induced functional recovery after stroke and identify a rehabilitation drug.
Authors: Okabe N; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA. Nokabe@mednet.ucla.edu., Wei X; Department of Neurosurgery, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Abumeri F; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Batac J; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Hovanesyan M; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Dai W; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Azarapetian S; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Campagna J; The Drug Discovery Lab, Mary S. Easton Center for Alzheimer's Disease Research, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Pilati N; Autifony Srl, Istituto di Ricerca Pediatrica Citta' della Speranza, Via Corso Stati Uniti, 4f, 35127, Padua, Italy., Marasco A; Autifony Srl, Istituto di Ricerca Pediatrica Citta' della Speranza, Via Corso Stati Uniti, 4f, 35127, Padua, Italy., Alvaro G; Autifony Srl, Istituto di Ricerca Pediatrica Citta' della Speranza, Via Corso Stati Uniti, 4f, 35127, Padua, Italy., Gunthorpe MJ; Autifony Therapeutics Limited, Stevenage Bioscience Catalyst, Stevenage, SG1 2FX, UK., Varghese J; The Drug Discovery Lab, Mary S. Easton Center for Alzheimer's Disease Research, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Cramer SC; Department of Neurology, UCLA, California Rehabilitation Institute, Los Angeles, CA, 90095, USA., Mody I; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.; Department of Physiology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA., Carmichael ST; Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA. SCarmichael@mednet.ucla.edu.
Source: Nature communications [Nat Commun] 2025 Mar 15; Vol. 16 (1), pp. 2556. Date of Electronic Publication: 2025 Mar 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-57860-0