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The impact of cardiorespiratory fitness on Alzheimer's disease biomarkers and their relationships with cognitive decline.

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Title: The impact of cardiorespiratory fitness on Alzheimer's disease biomarkers and their relationships with cognitive decline.
Authors: Paulsen AJ; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA., Driscoll I; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA., Breidenbach BM; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA., Glittenberg MP; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA., Lose SR; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA., Ma Y; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA., Sager MA; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA., Carlsson CM; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705., Gallagher CL; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.; Departmentof Neurology, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Madison, Wisconsin, 53705, USA., Hermann BP; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Departmentof Neurology, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Madison, Wisconsin, 53705, USA., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Box 100, 405 30 Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, SE-43180, Göteborg, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, 47 Bd de l'Hôpital, 75013, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, No.96, JinZhai Road Baohe District, Hefei, Anhui, 230026, P.R. China., Zetterberg H; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Box 100, 405 30 Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, SE-43180, Göteborg, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, Gower Street, London, WC1E 6BT, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Units 1501-1502, 1512-1518, 15/F Building 17W, 17 Science Park W Ave, Science Park, Hong Kong, PR China., Asthana S; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705., Johnson SC; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA., Betthauser TJ; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA., Christian BT; Department of Medical Physics, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 111 Highland Ave, Room 1005, Madison, Wisconsin, USA, 53705., Cook DB; William S. Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.; Department of Kinesiology, University of Wisconsin School of Education, 1300 University Avenue, 285 Medical Sciences Center, Madison, Wisconsin, USA, 53706., Okonkwo OC; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Mar 06. Date of Electronic Publication: 2025 Mar 06.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: The impact of cardiorespiratory fitness on Alzheimer's disease biomarkers and their relationships with cognitive decline.
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  Data: <searchLink fieldCode="AU" term="%22Paulsen+AJ%22">Paulsen AJ</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.<br /><searchLink fieldCode="AU" term="%22Driscoll+I%22">Driscoll I</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.<br /><searchLink fieldCode="AU" term="%22Breidenbach+BM%22">Breidenbach BM</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.<br /><searchLink fieldCode="AU" term="%22Glittenberg+MP%22">Glittenberg MP</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.<br /><searchLink fieldCode="AU" term="%22Lose+SR%22">Lose SR</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.<br /><searchLink fieldCode="AU" term="%22Ma+Y%22">Ma Y</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.<br /><searchLink fieldCode="AU" term="%22Sager+MA%22">Sager MA</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.<br /><searchLink fieldCode="AU" term="%22Carlsson+CM%22">Carlsson CM</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.<br /><searchLink fieldCode="AU" term="%22Gallagher+CL%22">Gallagher CL</searchLink>; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.; Departmentof Neurology, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Madison, Wisconsin, 53705, USA.<br /><searchLink fieldCode="AU" term="%22Hermann+BP%22">Hermann BP</searchLink>; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Departmentof Neurology, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Madison, Wisconsin, 53705, USA.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Box 100, 405 30 Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, SE-43180, Göteborg, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, 47 Bd de l'Hôpital, 75013, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, No.96, JinZhai Road Baohe District, Hefei, Anhui, 230026, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Box 100, 405 30 Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, SE-43180, Göteborg, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, Gower Street, London, WC1E 6BT, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Units 1501-1502, 1512-1518, 15/F Building 17W, 17 Science Park W Ave, Science Park, Hong Kong, PR China.<br /><searchLink fieldCode="AU" term="%22Asthana+S%22">Asthana S</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.<br /><searchLink fieldCode="AU" term="%22Johnson+SC%22">Johnson SC</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.<br /><searchLink fieldCode="AU" term="%22Betthauser+TJ%22">Betthauser TJ</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.<br /><searchLink fieldCode="AU" term="%22Christian+BT%22">Christian BT</searchLink>; Department of Medical Physics, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 111 Highland Ave, Room 1005, Madison, Wisconsin, USA, 53705.<br /><searchLink fieldCode="AU" term="%22Cook+DB%22">Cook DB</searchLink>; William S. Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.; Department of Kinesiology, University of Wisconsin School of Education, 1300 University Avenue, 285 Medical Sciences Center, Madison, Wisconsin, USA, 53706.<br /><searchLink fieldCode="AU" term="%22Okonkwo+OC%22">Okonkwo OC</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, MC2420, Madison, Wisconsin, 53792, USA.; Wisconsin Alzheimer's Institute, 610 Walnut St, Suite 957, Madison, Wisconsin, 53726, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, 2500 Overlook Terrace, Madison, Wisconsin, USA, 53705.
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