Older more fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles.
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| Title: | Older more fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles. |
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| Authors: | Jarchow M; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Driscoll I; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA., Breidenbach BM; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA., Cook N; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA., Gallagher CL; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, Madison, WI, USA.; Department of Neurology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Johnson SC; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA., Asthana S; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, Madison, WI, USA., Hermann BP; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.; Department of Neurology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Sager MA; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, China., Zetterberg H; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Roche Diagnostics GmbH, Penzberg, Germany., Carlsson CM; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.; Department of Neurology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Kollmorgen G; Roche Diagnostics GmbH, Penzberg, Germany., Quijano-Rubio C; Roche Diagnostics International Ltd, Rotkreuz, Switzerland., Cook DB; Research Service, William S. Middleton VA Hospital, Madison, WI, USA.; Department of Kinesiology, School of Education, University of Wisconsin-Madison, Madison, WI, USA., Dubal DB; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, California, USA., Okonkwo OC; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA. |
| Source: | MedRxiv : the preprint server for health sciences [medRxiv] 2025 Mar 03. Date of Electronic Publication: 2025 Mar 03. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40093256 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Older more fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Jarchow+M%22">Jarchow M</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Driscoll+I%22">Driscoll I</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Breidenbach+BM%22">Breidenbach BM</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Cook+N%22">Cook N</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gallagher+CL%22">Gallagher CL</searchLink>; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, Madison, WI, USA.; Department of Neurology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+SC%22">Johnson SC</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Asthana+S%22">Asthana S</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.; Geriatric Research Education and Clinical Center, William S. Middleton VA Hospital, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Hermann+BP%22">Hermann BP</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.; Department of Neurology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Sager+MA%22">Sager MA</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Roche Diagnostics GmbH, Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Carlsson+CM%22">Carlsson CM</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA.; Department of Neurology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Kollmorgen+G%22">Kollmorgen G</searchLink>; Roche Diagnostics GmbH, Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Quijano-Rubio+C%22">Quijano-Rubio C</searchLink>; Roche Diagnostics International Ltd, Rotkreuz, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cook+DB%22">Cook DB</searchLink>; Research Service, William S. Middleton VA Hospital, Madison, WI, USA.; Department of Kinesiology, School of Education, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Dubal+DB%22">Dubal DB</searchLink>; Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Okonkwo+OC%22">Okonkwo OC</searchLink>; Wisconsin Alzheimer's Disease Research Center, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Alzheimer's Institute Madison, WI, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2025 Mar 03. <i>Date of Electronic Publication: </i>2025 Mar 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101767986 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>NLM ISO Abbreviation: </i>medRxiv <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40093256 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1101/2025.02.27.25323056 Languages: – Code: eng Text: English Titles: – TitleFull: Older more fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jarchow M – PersonEntity: Name: NameFull: Driscoll I – PersonEntity: Name: NameFull: Breidenbach BM – PersonEntity: Name: NameFull: Cook N – PersonEntity: Name: NameFull: Gallagher CL – PersonEntity: Name: NameFull: Johnson SC – PersonEntity: Name: NameFull: Asthana S – PersonEntity: Name: NameFull: Hermann BP – PersonEntity: Name: NameFull: Sager MA – PersonEntity: Name: NameFull: Blennow K – PersonEntity: Name: NameFull: Zetterberg H – PersonEntity: Name: NameFull: Carlsson CM – PersonEntity: Name: NameFull: Kollmorgen G – PersonEntity: Name: NameFull: Quijano-Rubio C – PersonEntity: Name: NameFull: Cook DB – PersonEntity: Name: NameFull: Dubal DB – PersonEntity: Name: NameFull: Okonkwo OC IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 03 Text: 2025 Mar 03 Type: published Y: 2025 Titles: – TitleFull: MedRxiv : the preprint server for health sciences Type: main |
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