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Liver-FDG-uptake augments early PET/CT prognostic value for CD19-targeted CAR-T cell therapy in diffuse large B cell lymphoma.

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Title: Liver-FDG-uptake augments early PET/CT prognostic value for CD19-targeted CAR-T cell therapy in diffuse large B cell lymphoma.
Authors: Beck M; Department of Nuclear Medicine, University Hospital of Erlangen, Friedrich-Alexander-Universität- Erlangen Nürnberg, Erlangen, Germany. michael.beck@uk-erlangen.de.; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany. michael.beck@uk-erlangen.de., Blumenberg V; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory for Translational Cancer Immunology, LMU Gene Center, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Bücklein VL; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory for Translational Cancer Immunology, LMU Gene Center, LMU Munich, Munich, Germany., Bundschuh RA; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Nuclear Medicine, Faculty of Medicine, University Hospital of Augsburg, Augsburg, Germany.; Department of Nuclear Medicine, University Hospital Carl Gustav Carus at the TU Dresden, Dresden, Germany., Harrer DC; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine III, Hematology and Medical Oncology, University Hospital of Regensburg, Regensburg, Germany., Hirschbühl K; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Hematology and Oncology, Medical Faculty, University of Augsburg, Augsburg, Germany., Jung J; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany., Kunz WG; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Menhart K; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany., Winkelmann M; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Yakushev I; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Nuclear Medicine, School of Medicine, TUM University Hospital, Technical University of Munich, Munich, Germany., Illert AL; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany., Eckstein M; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Pathology, University Hospital of Erlangen, Friedrich-Alexander-Universität- Erlangen Nürnberg, Erlangen, Germany., Völkl S; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität-Erlangen Nürnberg, Erlangen, Germany., Claus R; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Hematology and Oncology, Medical Faculty, University of Augsburg, Augsburg, Germany.; Pathology, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Hansmann L; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine III, Hematology and Medical Oncology, University Hospital of Regensburg, Regensburg, Germany., Hecker JS; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Translational Cancer Research, Technical University of Munich (TUM), TranslaTUM, Munich, Germany., Kuwert T; Department of Nuclear Medicine, University Hospital of Erlangen, Friedrich-Alexander-Universität- Erlangen Nürnberg, Erlangen, Germany.; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany., Mackensen A; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität-Erlangen Nürnberg, Erlangen, Germany., Subklewe M; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory for Translational Cancer Immunology, LMU Gene Center, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Hellwig D; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany., Müller F; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany. fabian.mueller@uk-erlangen.de.; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität-Erlangen Nürnberg, Erlangen, Germany. fabian.mueller@uk-erlangen.de.
Source: EJNMMI research [EJNMMI Res] 2025 Mar 17; Vol. 15 (1), pp. 25. Date of Electronic Publication: 2025 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Springer Berlin Country of Publication: Germany NLM ID: 101560946 Publication Model: Electronic Cited Medium: Print ISSN: 2191-219X (Print) Linking ISSN: 2191219X NLM ISO Abbreviation: EJNMMI Res Subsets: PubMed not MEDLINE
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  Data: Liver-FDG-uptake augments early PET/CT prognostic value for CD19-targeted CAR-T cell therapy in diffuse large B cell lymphoma.
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  Data: <searchLink fieldCode="AU" term="%22Beck+M%22">Beck M</searchLink>; Department of Nuclear Medicine, University Hospital of Erlangen, Friedrich-Alexander-Universität- Erlangen Nürnberg, Erlangen, Germany. michael.beck@uk-erlangen.de.; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany. michael.beck@uk-erlangen.de.<br /><searchLink fieldCode="AU" term="%22Blumenberg+V%22">Blumenberg V</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory for Translational Cancer Immunology, LMU Gene Center, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bücklein+VL%22">Bücklein VL</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory for Translational Cancer Immunology, LMU Gene Center, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bundschuh+RA%22">Bundschuh RA</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Nuclear Medicine, Faculty of Medicine, University Hospital of Augsburg, Augsburg, Germany.; Department of Nuclear Medicine, University Hospital Carl Gustav Carus at the TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Harrer+DC%22">Harrer DC</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine III, Hematology and Medical Oncology, University Hospital of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hirschbühl+K%22">Hirschbühl K</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Hematology and Oncology, Medical Faculty, University of Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jung+J%22">Jung J</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kunz+WG%22">Kunz WG</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Menhart+K%22">Menhart K</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Winkelmann+M%22">Winkelmann M</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Yakushev+I%22">Yakushev I</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Nuclear Medicine, School of Medicine, TUM University Hospital, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Illert+AL%22">Illert AL</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Eckstein+M%22">Eckstein M</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Pathology, University Hospital of Erlangen, Friedrich-Alexander-Universität- Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Völkl+S%22">Völkl S</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität-Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Claus+R%22">Claus R</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Hematology and Oncology, Medical Faculty, University of Augsburg, Augsburg, Germany.; Pathology, Faculty of Medicine, University of Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hansmann+L%22">Hansmann L</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine III, Hematology and Medical Oncology, University Hospital of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hecker+JS%22">Hecker JS</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Translational Cancer Research, Technical University of Munich (TUM), TranslaTUM, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kuwert+T%22">Kuwert T</searchLink>; Department of Nuclear Medicine, University Hospital of Erlangen, Friedrich-Alexander-Universität- Erlangen Nürnberg, Erlangen, Germany.; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.<br /><searchLink fieldCode="AU" term="%22Mackensen+A%22">Mackensen A</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität-Erlangen Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Subklewe+M%22">Subklewe M</searchLink>; Bavarian Cancer Research Center, Resp. Site (Augsburg, LMU Munich, TUM Munich, Erlangen, Regensburg), Germany.; Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory for Translational Cancer Immunology, LMU Gene Center, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hellwig+D%22">Hellwig D</searchLink>; Bavarian Cancer Research Center, Resp. 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