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Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells.

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Title: Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells.
Authors: Auddino S; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Aiello E; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Grieco GE; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Fignani D; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Licata G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Bruttini M; Tuscany Centre for Precision Medicine (CReMeP), Siena, Italy., Mori A; Tuscany Centre for Precision Medicine (CReMeP), Siena, Italy., Berteramo AF; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Pedace E; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Nigi L; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Formichi C; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy., Guay C; Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland., Quero G; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Chirurgia Digestiva, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Tondolo V; General Surgery Unit, Fatebenefratelli Isola Tiberina-Gemelli Isola, Rome, Italy., Di Giuseppe G; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Soldovieri L; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Ciccarelli G; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Mari A; Institute of Neuroscience, National Research Council, Padua, Italy., Giaccari A; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Mezza T; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Po A; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Regazzi R; Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland.; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy. francesco.dotta@unisi.it.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy. francesco.dotta@unisi.it.; Tuscany Centre for Precision Medicine (CReMeP), Siena, Italy. francesco.dotta@unisi.it., Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.
Source: Diabetologia [Diabetologia] 2025 Jun; Vol. 68 (6), pp. 1261-1278. Date of Electronic Publication: 2025 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells.
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  Data: <searchLink fieldCode="AU" term="%22Auddino+S%22">Auddino S</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Aiello+E%22">Aiello E</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Grieco+GE%22">Grieco GE</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Fignani+D%22">Fignani D</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Licata+G%22">Licata G</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Bruttini+M%22">Bruttini M</searchLink>; Tuscany Centre for Precision Medicine (CReMeP), Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Mori+A%22">Mori A</searchLink>; Tuscany Centre for Precision Medicine (CReMeP), Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Berteramo+AF%22">Berteramo AF</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Pedace+E%22">Pedace E</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Nigi+L%22">Nigi L</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Formichi+C%22">Formichi C</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Guay+C%22">Guay C</searchLink>; Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Quero+G%22">Quero G</searchLink>; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Chirurgia Digestiva, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Tondolo+V%22">Tondolo V</searchLink>; General Surgery Unit, Fatebenefratelli Isola Tiberina-Gemelli Isola, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Giuseppe+G%22">Di Giuseppe G</searchLink>; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Soldovieri+L%22">Soldovieri L</searchLink>; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ciccarelli+G%22">Ciccarelli G</searchLink>; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mari+A%22">Mari A</searchLink>; Institute of Neuroscience, National Research Council, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Giaccari+A%22">Giaccari A</searchLink>; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mezza+T%22">Mezza T</searchLink>; Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.; Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Po+A%22">Po A</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Regazzi+R%22">Regazzi R</searchLink>; Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland.; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dotta+F%22">Dotta F</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy. francesco.dotta@unisi.it.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy. francesco.dotta@unisi.it.; Tuscany Centre for Precision Medicine (CReMeP), Siena, Italy. francesco.dotta@unisi.it.<br /><searchLink fieldCode="AU" term="%22Sebastiani+G%22">Sebastiani G</searchLink>; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS c/o Toscana Life Science, Siena, Italy.
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