CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma.
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| Title: | CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma. |
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| Authors: | Strassheimer F; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Elleringmann P; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Ludmirski G; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany., Roller B; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Macas J; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany., Alekseeva T; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Cakmak P; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Goethe University, Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany., Aliraj B; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, Institute of Biochemistry I, Faculty of Medicine, Frankfurt, Germany., Krenzlin H; University Medical Center Mainz, Department of Neurosurgery, Mainz, Germany., Demes MC; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, Dr. Senckenberg Institute of Pathology, Goethe University Hospital, Frankfurt, Germany., Mildenberger IC; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Department of Neurology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Tonn T; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Institute for Transfusion Medicine and Immunohematology, German Red Cross Blood Donation Service Baden-Württemberg-Hessen and Goethe University Hospital, Frankfurt, Germany., Weber KJ; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Goethe University, Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany., Reiss Y; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Goethe University, Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany., Plate KH; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Goethe University, Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany., Weigert A; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Goethe University, Institute of Biochemistry I, Faculty of Medicine, Frankfurt, Germany., Wels WS; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Steinbach JP; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Burger MC; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany. burger@med.uni-frankfurt.de.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. burger@med.uni-frankfurt.de.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany. burger@med.uni-frankfurt.de. |
| Source: | British journal of cancer [Br J Cancer] 2025 May; Vol. 132 (9), pp. 849-860. Date of Electronic Publication: 2025 Mar 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40102596 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Strassheimer+F%22">Strassheimer F</searchLink>; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Elleringmann+P%22">Elleringmann P</searchLink>; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ludmirski+G%22">Ludmirski G</searchLink>; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Roller+B%22">Roller B</searchLink>; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Macas+J%22">Macas J</searchLink>; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Goethe University, Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Alekseeva+T%22">Alekseeva T</searchLink>; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Cakmak+P%22">Cakmak P</searchLink>; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; 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German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Goethe University, Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Weigert+A%22">Weigert A</searchLink>; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Goethe University, Institute of Biochemistry I, Faculty of Medicine, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Wels+WS%22">Wels WS</searchLink>; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Steinbach+JP%22">Steinbach JP</searchLink>; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Burger+MC%22">Burger MC</searchLink>; Goethe University, Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany. burger@med.uni-frankfurt.de.; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. burger@med.uni-frankfurt.de.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany. burger@med.uni-frankfurt.de. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2025 May; Vol. 132 (9), pp. 849-860. <i>Date of Electronic Publication: </i>2025 Mar 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40102596 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41416-025-02977-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 849 Titles: – TitleFull: CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Strassheimer F – PersonEntity: Name: NameFull: Elleringmann P – PersonEntity: Name: NameFull: Ludmirski G – PersonEntity: Name: NameFull: Roller B – PersonEntity: Name: NameFull: Macas J – PersonEntity: Name: NameFull: Alekseeva T – PersonEntity: Name: NameFull: Cakmak P – PersonEntity: Name: NameFull: Aliraj B – PersonEntity: Name: NameFull: Krenzlin H – PersonEntity: Name: NameFull: Demes MC – PersonEntity: Name: NameFull: Mildenberger IC – PersonEntity: Name: NameFull: Tonn T – PersonEntity: Name: NameFull: Weber KJ – PersonEntity: Name: NameFull: Reiss Y – PersonEntity: Name: NameFull: Plate KH – PersonEntity: Name: NameFull: Weigert A – PersonEntity: Name: NameFull: Wels WS – PersonEntity: Name: NameFull: Steinbach JP – PersonEntity: Name: NameFull: Burger MC IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2025 May Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1532-1827 Numbering: – Type: volume Value: 132 – Type: issue Value: 9 Titles: – TitleFull: British journal of cancer Type: main |
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