CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system.
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| Title: | CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system. |
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| Authors: | Salman A; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. ahmed.salman@ndcn.ox.ac.uk., Song WK; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Gangnum Yonsei Eye Clinic, Seoul, Republic of South Korea., Storm T; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., McClements ME; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., MacLaren RE; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. maclaren@eye.ox.ac.uk.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. maclaren@eye.ox.ac.uk. |
| Source: | Gene therapy [Gene Ther] 2025 Mar; Vol. 32 (2), pp. 132-141. Date of Electronic Publication: 2025 Mar 18. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1476-5462 |
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| DOI: | 10.1038/s41434-025-00522-z |
