Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction - 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators' viewpoint.

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Title: Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction - 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators' viewpoint.
Authors: Kubica J; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland., Adamski P; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland., Badariene J; Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Bonaca M; CPC Clinical Research, Aurora, United States., Buszman P; Cardiology Department, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland; Center for Cardiology and Cardiac Surgery of American Heart of Poland, Bielsko-Biała, Poland., Gabulova R; Teaching-Therapeutical Hospital, Azerbaijan Medical University, Baku, Azerbaijan., Gajda R; Gajda-Med District Hospital in Pultusk, Poland., Geisler T; Medical Clinic III, University Hospital Tübingen, Tübingen, Germany., Gil R; Department of Invasive Cardiology, Centre of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland., Gorog DA; Postgraduate Medical School, University of Hertfordshire, Hertfordshire, United Kingdom.; Faculty of Medicine, National Heart and Lung Institute, London, United Kingdom.; Cardiology Department, Royal Brompton & Harefield NHS Trust, Part of Guys and St Thomas' Hospitals, London, United Kingdom., Gurbel PA; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Baltimore, Maryland, United States., Hajdukiewicz T; Department of Cardiology, Provincial Hospital, Elblag, Poland., Hudzik B; Department of Metabolic Disease Prevention, Faculty of Public Health in Bytom, Medical University of Silesia, Bytom, Poland.; Third Department of Cardiology, Silesian Center for Heart Disease, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland., James S; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Jeong YH; CAU Thrombosis and Biomarker Center, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Republic of Korea.; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea., Kern A; Department of Cardiology and Internal Medicine, Medical Faculty, University of Warmia and Mazury in Olsztyn, Poland., Kochman W; The National Institute of Cardiology, Department of Cardiology, Bielanski Hospital, Warsaw, Poland., Kubica A; Department of Cardiac Rehabilitation and Health Promotion, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland., Kuliczkowski W; Institute of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland., Magielski P; Interventional Cardiology and Cardiovascular Medicine Research, Department of Cardiology and Internal Medicine, Nicolaus Copernicus University, Bydgoszcz, Poland., Niezgoda P; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland. piotr.niezgoda1986@gmail.com., Ostrowska M; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland., Raggi P; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada., Rahimov U; Department of Cardiology, Baku Medical Plaza, Baku, Azerbaijan., Skonieczny G; Department of Cardiology and Intensive Cardiological Care, Rydygier Provincial Hospital, Torun, Poland., Siller-Matula JM; Department of Cardiology, Medical University of Vienna, Vienna, Austria., Specchia G; Department of Cardiology, Policlinico di Monza, Monza, Italy., Szarpak Ł; Department of Clinical Research and Development, LUXMED Group, Warsaw, Poland., Szymański P; Department of Cardiology, Interventional Cardiology and Electrophysiology with Cardiac Intensive Care Unit, Tertiary Care Hospital in Grudziadz, Poland., Tantry U; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Baltimore, Maryland, United States., Umińska J; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland., Navarese EP; Clinical and Interventional Cardiology, Sassari University Hospital, Italy.
Source: Cardiology journal [Cardiol J] 2025; Vol. 32 (2), pp. 189-194. Date of Electronic Publication: 2025 Mar 20.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Via Medica Country of Publication: Poland NLM ID: 101392712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1898-018X (Electronic) Linking ISSN: 1898018X NLM ISO Abbreviation: Cardiol J Subsets: MEDLINE
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  Data: Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction - 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators' viewpoint.
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  Data: <searchLink fieldCode="AU" term="%22Kubica+J%22">Kubica J</searchLink>; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.<br /><searchLink fieldCode="AU" term="%22Adamski+P%22">Adamski P</searchLink>; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.<br /><searchLink fieldCode="AU" term="%22Badariene+J%22">Badariene J</searchLink>; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.<br /><searchLink fieldCode="AU" term="%22Bonaca+M%22">Bonaca M</searchLink>; CPC Clinical Research, Aurora, United States.<br /><searchLink fieldCode="AU" term="%22Buszman+P%22">Buszman P</searchLink>; Cardiology Department, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland; Center for Cardiology and Cardiac Surgery of American Heart of Poland, Bielsko-Biała, Poland.<br /><searchLink fieldCode="AU" term="%22Gabulova+R%22">Gabulova R</searchLink>; Teaching-Therapeutical Hospital, Azerbaijan Medical University, Baku, Azerbaijan.<br /><searchLink fieldCode="AU" term="%22Gajda+R%22">Gajda R</searchLink>; Gajda-Med District Hospital in Pultusk, Poland.<br /><searchLink fieldCode="AU" term="%22Geisler+T%22">Geisler T</searchLink>; Medical Clinic III, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Gil+R%22">Gil R</searchLink>; Department of Invasive Cardiology, Centre of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Gorog+DA%22">Gorog DA</searchLink>; Postgraduate Medical School, University of Hertfordshire, Hertfordshire, United Kingdom.; Faculty of Medicine, National Heart and Lung Institute, London, United Kingdom.; Cardiology Department, Royal Brompton & Harefield NHS Trust, Part of Guys and St Thomas' Hospitals, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gurbel+PA%22">Gurbel PA</searchLink>; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Hajdukiewicz+T%22">Hajdukiewicz T</searchLink>; Department of Cardiology, Provincial Hospital, Elblag, Poland.<br /><searchLink fieldCode="AU" term="%22Hudzik+B%22">Hudzik B</searchLink>; Department of Metabolic Disease Prevention, Faculty of Public Health in Bytom, Medical University of Silesia, Bytom, Poland.; Third Department of Cardiology, Silesian Center for Heart Disease, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Zabrze, Poland.<br /><searchLink fieldCode="AU" term="%22James+S%22">James S</searchLink>; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Jeong+YH%22">Jeong YH</searchLink>; CAU Thrombosis and Biomarker Center, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Republic of Korea.; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kern+A%22">Kern A</searchLink>; Department of Cardiology and Internal Medicine, Medical Faculty, University of Warmia and Mazury in Olsztyn, Poland.<br /><searchLink fieldCode="AU" term="%22Kochman+W%22">Kochman W</searchLink>; The National Institute of Cardiology, Department of Cardiology, Bielanski Hospital, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Kubica+A%22">Kubica A</searchLink>; Department of Cardiac Rehabilitation and Health Promotion, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.<br /><searchLink fieldCode="AU" term="%22Kuliczkowski+W%22">Kuliczkowski W</searchLink>; Institute of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Magielski+P%22">Magielski P</searchLink>; Interventional Cardiology and Cardiovascular Medicine Research, Department of Cardiology and Internal Medicine, Nicolaus Copernicus University, Bydgoszcz, Poland.<br /><searchLink fieldCode="AU" term="%22Niezgoda+P%22">Niezgoda P</searchLink>; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland. piotr.niezgoda1986@gmail.com.<br /><searchLink fieldCode="AU" term="%22Ostrowska+M%22">Ostrowska M</searchLink>; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.<br /><searchLink fieldCode="AU" term="%22Raggi+P%22">Raggi P</searchLink>; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Rahimov+U%22">Rahimov U</searchLink>; Department of Cardiology, Baku Medical Plaza, Baku, Azerbaijan.<br /><searchLink fieldCode="AU" term="%22Skonieczny+G%22">Skonieczny G</searchLink>; Department of Cardiology and Intensive Cardiological Care, Rydygier Provincial Hospital, Torun, Poland.<br /><searchLink fieldCode="AU" term="%22Siller-Matula+JM%22">Siller-Matula JM</searchLink>; Department of Cardiology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Specchia+G%22">Specchia G</searchLink>; Department of Cardiology, Policlinico di Monza, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Szarpak+Ł%22">Szarpak Ł</searchLink>; Department of Clinical Research and Development, LUXMED Group, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Szymański+P%22">Szymański P</searchLink>; Department of Cardiology, Interventional Cardiology and Electrophysiology with Cardiac Intensive Care Unit, Tertiary Care Hospital in Grudziadz, Poland.<br /><searchLink fieldCode="AU" term="%22Tantry+U%22">Tantry U</searchLink>; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Umińska+J%22">Umińska J</searchLink>; Department of Cardiology and Internal Medicine, L. Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.<br /><searchLink fieldCode="AU" term="%22Navarese+EP%22">Navarese EP</searchLink>; Clinical and Interventional Cardiology, Sassari University Hospital, Italy.
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