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PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway-Deficient Acute Myeloid Leukemia.

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Title: PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway-Deficient Acute Myeloid Leukemia.
Authors: Sheth AS; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Chan KK; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Liu S; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Wan J; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana., Angus SP; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Rhodes SD; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Mitchell DK; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Davis C; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Ridinger M; Cardiff Oncology, San Diego, California., Croucher PJ; Cardiff Oncology, San Diego, California., Zeidan AM; Yale University and Yale Cancer Center, New Haven, Connecticut., Wijeratne A; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana., Qian S; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Tran NT; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana., Sierra Potchanant EA; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
Source: Cancer research communications [Cancer Res Commun] 2025 Apr 01; Vol. 5 (4), pp. 648-667.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway-Deficient Acute Myeloid Leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Sheth+AS%22">Sheth AS</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Chan+KK%22">Chan KK</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Wan+J%22">Wan J</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Angus+SP%22">Angus SP</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Rhodes+SD%22">Rhodes SD</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Mitchell+DK%22">Mitchell DK</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Davis+C%22">Davis C</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Ridinger+M%22">Ridinger M</searchLink>; Cardiff Oncology, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Croucher+PJ%22">Croucher PJ</searchLink>; Cardiff Oncology, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Zeidan+AM%22">Zeidan AM</searchLink>; Yale University and Yale Cancer Center, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Wijeratne+A%22">Wijeratne A</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Qian+S%22">Qian S</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Tran+NT%22">Tran NT</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Sierra+Potchanant+EA%22">Sierra Potchanant EA</searchLink>; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
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  Data: <searchLink fieldCode="JN" term="%229918281580506676%22">Cancer research communications</searchLink> [Cancer Res Commun] 2025 Apr 01; Vol. 5 (4), pp. 648-667.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918281580506676 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2767-9764 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227679764%22">27679764 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Res Commun <i>Subsets: </i>MEDLINE
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              Text: 2025 Apr 01
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