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APOE genotype determines cell-type-specific pathological landscape of Alzheimer's disease.

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Title: APOE genotype determines cell-type-specific pathological landscape of Alzheimer's disease.
Authors: Li Z; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Martens YA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Ren Y; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL 32224, USA., Jin Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Sekiya H; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Doss SV; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Kouri N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Castanedes-Casey M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Christensen TA; Microscopy and Cell Analysis Core, Mayo Clinic, Rochester, MN 55905, USA., Miller Nevalainen LB; Microscopy and Cell Analysis Core, Mayo Clinic, Rochester, MN 55905, USA., Takegami N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Chen K; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Liu CC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Soto-Beasley A; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Boon BDC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Labuzan SA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Ikezu TC; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL 32224, USA., Chen Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Bartkowiak AD; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Xhafkollari G; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Wetmore AM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, USA., Reichard RR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA., Kanekiyo T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA., Bu G; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. Electronic address: gbu@ust.hk., Zhao N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. Electronic address: zhao.na@mayo.edu.
Source: Neuron [Neuron] 2025 May 07; Vol. 113 (9), pp. 1380-1397.e7. Date of Electronic Publication: 2025 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: APOE genotype determines cell-type-specific pathological landscape of Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Martens+YA%22">Martens YA</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Jin+Y%22">Jin Y</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Sekiya+H%22">Sekiya H</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Doss+SV%22">Doss SV</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Kouri+N%22">Kouri N</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Castanedes-Casey+M%22">Castanedes-Casey M</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Christensen+TA%22">Christensen TA</searchLink>; Microscopy and Cell Analysis Core, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Miller+Nevalainen+LB%22">Miller Nevalainen LB</searchLink>; Microscopy and Cell Analysis Core, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Takegami+N%22">Takegami N</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Liu+CC%22">Liu CC</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Soto-Beasley+A%22">Soto-Beasley A</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Boon+BDC%22">Boon BDC</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Labuzan+SA%22">Labuzan SA</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Ikezu+TC%22">Ikezu TC</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Bartkowiak+AD%22">Bartkowiak AD</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Xhafkollari+G%22">Xhafkollari G</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Wetmore+AM%22">Wetmore AM</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Bennett+DA%22">Bennett DA</searchLink>; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL 60612, USA.<br /><searchLink fieldCode="AU" term="%22Reichard+RR%22">Reichard RR</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Petersen+RC%22">Petersen RC</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Kanekiyo+T%22">Kanekiyo T</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Ross+OA%22">Ross OA</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Murray+ME%22">Murray ME</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Dickson+DW%22">Dickson DW</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.<br /><searchLink fieldCode="AU" term="%22Bu+G%22">Bu G</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. Electronic address: gbu@ust.hk.<br /><searchLink fieldCode="AU" term="%22Zhao+N%22">Zhao N</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. Electronic address: zhao.na@mayo.edu.
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  Data: <searchLink fieldCode="JN" term="%228809320%22">Neuron</searchLink> [Neuron] 2025 May 07; Vol. 113 (9), pp. 1380-1397.e7. <i>Date of Electronic Publication: </i>2025 Mar 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8809320 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4199 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208966273%22">08966273 </searchLink><i>NLM ISO Abbreviation: </i>Neuron <i>Subsets: </i>MEDLINE
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