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The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy.

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Title: The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy.
Authors: Vogler M; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany. m.vogler@kinderkrebsstiftung-frankfurt.de.; German Cancer Consortium (DKTK) partner site Frankfurt/Mainz, a partnership between DKFZ and University Hospital Frankfurt, Frankfurt am Main, Germany. m.vogler@kinderkrebsstiftung-frankfurt.de.; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany. m.vogler@kinderkrebsstiftung-frankfurt.de., Braun Y; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany.; Department of Pediatric Surgery, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany., Smith VM; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, University of Leicester, Leicester, UK., Westhoff MA; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany., Pereira RS; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany., Pieper NM; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany., Anders M; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany., Callens M; KU Leuven, Lab. Molecular & Cellular Signaling, Dep. Cellular & Molecular Medicine, and Leuven Kankerinstituut (LKI), Leuven, Belgium., Vervliet T; KU Leuven, Lab. Molecular & Cellular Signaling, Dep. Cellular & Molecular Medicine, and Leuven Kankerinstituut (LKI), Leuven, Belgium., Abbas M; Mechanisms of Cancer and Ageing Laboratory, Department of Molecular and Cell Biology, University of Leicester, Leicester, UK., Macip S; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, University of Leicester, Leicester, UK.; Mechanisms of Cancer and Ageing Laboratory, Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.; Josep Carreras Leukaemia Research Institute, Badalona, Spain.; FoodLab, Faculty of Health Sciences, Universitat Oberta de Catalunya, Barcelona, Spain., Schmid R; Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.; Institute for Structural and Chemical Biology, University of Leicester, Leicester, UK., Bultynck G; KU Leuven, Lab. Molecular & Cellular Signaling, Dep. Cellular & Molecular Medicine, and Leuven Kankerinstituut (LKI), Leuven, Belgium., Dyer MJ; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, University of Leicester, Leicester, UK.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Mar 21; Vol. 10 (1), pp. 91. Date of Electronic Publication: 2025 Mar 21.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy.
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  Data: <searchLink fieldCode="AU" term="%22Vogler+M%22">Vogler M</searchLink>; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany. m.vogler@kinderkrebsstiftung-frankfurt.de.; German Cancer Consortium (DKTK) partner site Frankfurt/Mainz, a partnership between DKFZ and University Hospital Frankfurt, Frankfurt am Main, Germany. m.vogler@kinderkrebsstiftung-frankfurt.de.; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany. m.vogler@kinderkrebsstiftung-frankfurt.de.<br /><searchLink fieldCode="AU" term="%22Braun+Y%22">Braun Y</searchLink>; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany.; Department of Pediatric Surgery, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Smith+VM%22">Smith VM</searchLink>; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Westhoff+MA%22">Westhoff MA</searchLink>; Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Pereira+RS%22">Pereira RS</searchLink>; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Pieper+NM%22">Pieper NM</searchLink>; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Anders+M%22">Anders M</searchLink>; Goethe University Frankfurt, Institute for Experimental Pediatric Hematology and Oncology, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Callens+M%22">Callens M</searchLink>; KU Leuven, Lab. Molecular & Cellular Signaling, Dep. Cellular & Molecular Medicine, and Leuven Kankerinstituut (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vervliet+T%22">Vervliet T</searchLink>; KU Leuven, Lab. Molecular & Cellular Signaling, Dep. Cellular & Molecular Medicine, and Leuven Kankerinstituut (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Abbas+M%22">Abbas M</searchLink>; Mechanisms of Cancer and Ageing Laboratory, Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Macip+S%22">Macip S</searchLink>; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, University of Leicester, Leicester, UK.; Mechanisms of Cancer and Ageing Laboratory, Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.; Josep Carreras Leukaemia Research Institute, Badalona, Spain.; FoodLab, Faculty of Health Sciences, Universitat Oberta de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Schmid+R%22">Schmid R</searchLink>; Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.; Institute for Structural and Chemical Biology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Bultynck+G%22">Bultynck G</searchLink>; KU Leuven, Lab. Molecular & Cellular Signaling, Dep. Cellular & Molecular Medicine, and Leuven Kankerinstituut (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Dyer+MJ%22">Dyer MJ</searchLink>; The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, University of Leicester, Leicester, UK.
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