Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs.
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| Title: | Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs. |
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| Authors: | Gremke N; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany. Gremken@staff.uni-marburg.de.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany. Gremken@staff.uni-marburg.de., Besong I; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Stroh A; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., von Wichert L; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Witt M; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Elmshäuser S; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany., Wanzel M; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany., Fromm MF; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; FAU NeW - Research Center New Bioactive Compounds, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Taudte RV; Core Facility for Metabolomics, Philipps University, Marburg, Germany., Schmatloch S; Elisabeth Hospital Kassel, Kassel, Germany., Karn T; UCT Frankfurt-Marburg, Department of Gynecology and Obstetrics, Goethe University, Frankfurt, Germany., Reinisch M; Breast Unit, University Hospital Mannheim, Mannheim, Germany.; Department of Gynecology with Breast Center, University Medicine Berlin, Berlin, Germany., Hirmas N; German Breast Group (GBG), Neu-Isenburg, Germany., Loibl S; German Breast Group (GBG), Neu-Isenburg, Germany., Wündisch T; UCT Frankfurt-Marburg, Comprehensive Cancer Center Marburg, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Litmeyer AS; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Jank P; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Denkert C; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Griewing S; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Wagner U; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Stiewe T; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Genomics Core Facility, Philipps-University, Marburg, Germany.; Institute of Lung Health, Justus Liebig University, Gießen, Germany. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Mar 21; Vol. 10 (1), pp. 92. Date of Electronic Publication: 2025 Mar 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2059-3635 |
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| DOI: | 10.1038/s41392-025-02180-4 |