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Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs.

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Title: Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs.
Authors: Gremke N; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany. Gremken@staff.uni-marburg.de.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany. Gremken@staff.uni-marburg.de., Besong I; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Stroh A; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., von Wichert L; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Witt M; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Elmshäuser S; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany., Wanzel M; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany., Fromm MF; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; FAU NeW - Research Center New Bioactive Compounds, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Taudte RV; Core Facility for Metabolomics, Philipps University, Marburg, Germany., Schmatloch S; Elisabeth Hospital Kassel, Kassel, Germany., Karn T; UCT Frankfurt-Marburg, Department of Gynecology and Obstetrics, Goethe University, Frankfurt, Germany., Reinisch M; Breast Unit, University Hospital Mannheim, Mannheim, Germany.; Department of Gynecology with Breast Center, University Medicine Berlin, Berlin, Germany., Hirmas N; German Breast Group (GBG), Neu-Isenburg, Germany., Loibl S; German Breast Group (GBG), Neu-Isenburg, Germany., Wündisch T; UCT Frankfurt-Marburg, Comprehensive Cancer Center Marburg, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Litmeyer AS; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Jank P; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Denkert C; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Griewing S; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Wagner U; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany., Stiewe T; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Genomics Core Facility, Philipps-University, Marburg, Germany.; Institute of Lung Health, Justus Liebig University, Gießen, Germany.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Mar 21; Vol. 10 (1), pp. 92. Date of Electronic Publication: 2025 Mar 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs.
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  Data: <searchLink fieldCode="AU" term="%22Gremke+N%22">Gremke N</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany. Gremken@staff.uni-marburg.de.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany. Gremken@staff.uni-marburg.de.<br /><searchLink fieldCode="AU" term="%22Besong+I%22">Besong I</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stroh+A%22">Stroh A</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Wichert+L%22">von Wichert L</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Witt+M%22">Witt M</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Elmshäuser+S%22">Elmshäuser S</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wanzel+M%22">Wanzel M</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fromm+MF%22">Fromm MF</searchLink>; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; FAU NeW - Research Center New Bioactive Compounds, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Taudte+RV%22">Taudte RV</searchLink>; Core Facility for Metabolomics, Philipps University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmatloch+S%22">Schmatloch S</searchLink>; Elisabeth Hospital Kassel, Kassel, Germany.<br /><searchLink fieldCode="AU" term="%22Karn+T%22">Karn T</searchLink>; UCT Frankfurt-Marburg, Department of Gynecology and Obstetrics, Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Reinisch+M%22">Reinisch M</searchLink>; Breast Unit, University Hospital Mannheim, Mannheim, Germany.; Department of Gynecology with Breast Center, University Medicine Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hirmas+N%22">Hirmas N</searchLink>; German Breast Group (GBG), Neu-Isenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Loibl+S%22">Loibl S</searchLink>; German Breast Group (GBG), Neu-Isenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wündisch+T%22">Wündisch T</searchLink>; UCT Frankfurt-Marburg, Comprehensive Cancer Center Marburg, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Litmeyer+AS%22">Litmeyer AS</searchLink>; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jank+P%22">Jank P</searchLink>; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Denkert+C%22">Denkert C</searchLink>; Institute of Pathology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Griewing+S%22">Griewing S</searchLink>; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+U%22">Wagner U</searchLink>; Department of Gynecology, Gynecological Endocrinology and Oncology, University Hospital Gießen and Marburg Campus Marburg, Philipps-University, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stiewe+T%22">Stiewe T</searchLink>; Institute of Molecular Oncology, Universities of Gießen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Philipps-University, Marburg, Germany.; Genomics Core Facility, Philipps-University, Marburg, Germany.; Institute of Lung Health, Justus Liebig University, Gießen, Germany.
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