Comparison of enriched charge variants from different anti-CD3 bispecific antibodies reveals differential susceptibility of each bispecific arm to post-translational modification.
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| Title: | Comparison of enriched charge variants from different anti-CD3 bispecific antibodies reveals differential susceptibility of each bispecific arm to post-translational modification. |
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| Authors: | Nguyen JB; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Liu S; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Howie DA; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Oberholtzer ZR; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Ong ET; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Rao R; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Prinston JE; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Dikiy I; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Wu J; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Wu Z; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Zhao Y; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Li M; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Molden R; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Molina G; Therapeutic Proteins, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Provoncha K; Therapeutic Proteins, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Sandu C; Therapeutic Proteins, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Qiu H; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Li N; Analytical Chemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Matousek W; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Rosconi MP; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA., Pyles EA; Protein Biochemistry, Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA. |
| Source: | Protein science : a publication of the Protein Society [Protein Sci] 2025 Apr; Vol. 34 (4), pp. e70079. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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