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Serum Neurofilament Light Chain and Structural and Functional Nerve Fiber Loss in Painful and Painless Diabetic Polyneuropathy.

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Title: Serum Neurofilament Light Chain and Structural and Functional Nerve Fiber Loss in Painful and Painless Diabetic Polyneuropathy.
Authors: Määttä LL; Danish Pain Research Center, Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 165, J109, 8200 Aarhus, Denmark; Steno Diabetes Center Aarhus, Aarhus University Hospital, Palle Juul-Jensens Boulevard 11, 8200 Aarhus, Denmark; Medical Department, Horsens Regional Hospital, Sundvej 30, 8700 Horsens, Denmark. Electronic address: llm@clin.au.dk., Andersen ST; Steno Diabetes Center Aarhus, Aarhus University Hospital, Palle Juul-Jensens Boulevard 11, 8200 Aarhus, Denmark; Medical Department, Gødstrup Hospital, Hospitalsparken 15, 7400 Herning, Denmark. Electronic address: signe.toft.andersen@midt.rm.dk., Parkner T; Department of Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark. Electronic address: tina.parkner@auh.rm.dk., Hviid CVB; Department of Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark; Department of Clinical Biochemistry, Aalborg University Hospital, Hobrovej 18-22, 9000 Aalborg, Denmark. Electronic address: claus.hviid@auh.rm.dk., Witte DR; Steno Diabetes Center Aarhus, Aarhus University Hospital, Palle Juul-Jensens Boulevard 11, 8200 Aarhus, Denmark; Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus, Denmark. Electronic address: daniel.witte@ph.au.dk., John J; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: jishi.john@ndcn.ox.ac.uk., Pascal MMV; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: mathilde.pascal@ndcn.ox.ac.uk., Ferris E; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: eferris@hotmail.co.uk., Baskozos G; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: georgios.baskozos@ndcn.ox.ac.uk., Ramirez JD; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: juandiegoramirezrozo@gmail.com., Tesfaye S; Diabetes Research Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom. Electronic address: solomon.tesfaye@nhs.net., Shillo PR; Diabetes Research Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom. Electronic address: shillopr@yahoo.com., Rice ASC; Pain Research, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom. Electronic address: a.rice@imperial.ac.uk., Laycock HC; Pain Research, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom. Electronic address: helen.laycock@doctors.org.uk., Jensen TS; Danish Pain Research Center, Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 165, J109, 8200 Aarhus, Denmark. Electronic address: tsjensen@clin.au.dk., Bennett DL; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: david.bennett@ndcn.ox.ac.uk., Themistocleous AC; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: andreas.themistocleous@ndcn.ox.ac.uk.
Source: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2025 May; Vol. 223, pp. 112098. Date of Electronic Publication: 2025 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE
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  Data: Serum Neurofilament Light Chain and Structural and Functional Nerve Fiber Loss in Painful and Painless Diabetic Polyneuropathy.
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  Data: <searchLink fieldCode="AU" term="%22Määttä+LL%22">Määttä LL</searchLink>; Danish Pain Research Center, Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 165, J109, 8200 Aarhus, Denmark; Steno Diabetes Center Aarhus, Aarhus University Hospital, Palle Juul-Jensens Boulevard 11, 8200 Aarhus, Denmark; Medical Department, Horsens Regional Hospital, Sundvej 30, 8700 Horsens, Denmark. Electronic address: llm@clin.au.dk.<br /><searchLink fieldCode="AU" term="%22Andersen+ST%22">Andersen ST</searchLink>; Steno Diabetes Center Aarhus, Aarhus University Hospital, Palle Juul-Jensens Boulevard 11, 8200 Aarhus, Denmark; Medical Department, Gødstrup Hospital, Hospitalsparken 15, 7400 Herning, Denmark. Electronic address: signe.toft.andersen@midt.rm.dk.<br /><searchLink fieldCode="AU" term="%22Parkner+T%22">Parkner T</searchLink>; Department of Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark. Electronic address: tina.parkner@auh.rm.dk.<br /><searchLink fieldCode="AU" term="%22Hviid+CVB%22">Hviid CVB</searchLink>; Department of Clinical Biochemistry, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus, Denmark; Department of Clinical Biochemistry, Aalborg University Hospital, Hobrovej 18-22, 9000 Aalborg, Denmark. Electronic address: claus.hviid@auh.rm.dk.<br /><searchLink fieldCode="AU" term="%22Witte+DR%22">Witte DR</searchLink>; Steno Diabetes Center Aarhus, Aarhus University Hospital, Palle Juul-Jensens Boulevard 11, 8200 Aarhus, Denmark; Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus, Denmark. Electronic address: daniel.witte@ph.au.dk.<br /><searchLink fieldCode="AU" term="%22John+J%22">John J</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: jishi.john@ndcn.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Pascal+MMV%22">Pascal MMV</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: mathilde.pascal@ndcn.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ferris+E%22">Ferris E</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: eferris@hotmail.co.uk.<br /><searchLink fieldCode="AU" term="%22Baskozos+G%22">Baskozos G</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: georgios.baskozos@ndcn.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ramirez+JD%22">Ramirez JD</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: juandiegoramirezrozo@gmail.com.<br /><searchLink fieldCode="AU" term="%22Tesfaye+S%22">Tesfaye S</searchLink>; Diabetes Research Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom. Electronic address: solomon.tesfaye@nhs.net.<br /><searchLink fieldCode="AU" term="%22Shillo+PR%22">Shillo PR</searchLink>; Diabetes Research Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom. Electronic address: shillopr@yahoo.com.<br /><searchLink fieldCode="AU" term="%22Rice+ASC%22">Rice ASC</searchLink>; Pain Research, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom. Electronic address: a.rice@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Laycock+HC%22">Laycock HC</searchLink>; Pain Research, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom. Electronic address: helen.laycock@doctors.org.uk.<br /><searchLink fieldCode="AU" term="%22Jensen+TS%22">Jensen TS</searchLink>; Danish Pain Research Center, Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 165, J109, 8200 Aarhus, Denmark. Electronic address: tsjensen@clin.au.dk.<br /><searchLink fieldCode="AU" term="%22Bennett+DL%22">Bennett DL</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: david.bennett@ndcn.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Themistocleous+AC%22">Themistocleous AC</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, United Kingdom. Electronic address: andreas.themistocleous@ndcn.ox.ac.uk.
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