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Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates.

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Title: Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates.
Authors: Detrille A; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Huvelle S; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.; Université Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale Paris-Saclay, Orsay, France., van Gils MJ; Department of Medical Microbiology and Infection Prevention of the Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands., Geara T; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Pascal Q; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Snitselaar J; Department of Medical Microbiology and Infection Prevention of the Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands., Bossevot L; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Cavarelli M; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Dereuddre-Bosquet N; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Relouzat F; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Contreras V; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Chapon C; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Caillé F; Université Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale Paris-Saclay, Orsay, France., Sanders RW; Department of Medical Microbiology and Infection Prevention of the Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands., Le Grand R; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France., Naninck T; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France. thibaut.naninck@cea.fr.
Source: Nature communications [Nat Commun] 2025 Mar 21; Vol. 16 (1), pp. 2816. Date of Electronic Publication: 2025 Mar 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates.
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  Data: <searchLink fieldCode="AU" term="%22Detrille+A%22">Detrille A</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Huvelle+S%22">Huvelle S</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.; Université Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale Paris-Saclay, Orsay, France.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; Department of Medical Microbiology and Infection Prevention of the Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Geara+T%22">Geara T</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Pascal+Q%22">Pascal Q</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Snitselaar+J%22">Snitselaar J</searchLink>; Department of Medical Microbiology and Infection Prevention of the Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bossevot+L%22">Bossevot L</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Cavarelli+M%22">Cavarelli M</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Dereuddre-Bosquet+N%22">Dereuddre-Bosquet N</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Relouzat+F%22">Relouzat F</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Contreras+V%22">Contreras V</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Chapon+C%22">Chapon C</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Caillé+F%22">Caillé F</searchLink>; Université Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale Paris-Saclay, Orsay, France.<br /><searchLink fieldCode="AU" term="%22Sanders+RW%22">Sanders RW</searchLink>; Department of Medical Microbiology and Infection Prevention of the Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Le+Grand+R%22">Le Grand R</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France.<br /><searchLink fieldCode="AU" term="%22Naninck+T%22">Naninck T</searchLink>; Université Paris-Saclay, Inserm, CEA, Center for Immunology of Viral, Auto-immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Fontenay-aux-Roses & Le Kremlin-Bicêtre, Fontenay-aux-Roses, France. thibaut.naninck@cea.fr.
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