In Vitro and In Vivo Pharmacokinetic Characterization of 7-Hydroxymitragynine, an Active Metabolite of Mitragynine, in Sprague-Dawley Rats.
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| Title: | In Vitro and In Vivo Pharmacokinetic Characterization of 7-Hydroxymitragynine, an Active Metabolite of Mitragynine, in Sprague-Dawley Rats. |
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| Authors: | Chiang YH; Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Drive Medical Sciences Building MSB P3-20B, Gainesville, FL, 32610, USA., Kanumuri SRR; Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Drive Medical Sciences Building MSB P3-20B, Gainesville, FL, 32610, USA.; Translational Drug Development Core, Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA., Kuntz MA; Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Drive Medical Sciences Building MSB P3-20B, Gainesville, FL, 32610, USA., Senetra AS; Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Drive Medical Sciences Building MSB P3-20B, Gainesville, FL, 32610, USA., Berthold EC; Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Drive Medical Sciences Building MSB P3-20B, Gainesville, FL, 32610, USA., Kamble SH; Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Drive Medical Sciences Building MSB P3-20B, Gainesville, FL, 32610, USA., Mukhopadhyay S; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, USA., Hampson AJ; Division of Therapeutics and Medical Consequences, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA., McCurdy CR; Translational Drug Development Core, Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA.; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL, USA., Sharma A; Department of Pharmaceutics, College of Pharmacy, University of Florida, 1345 Center Drive Medical Sciences Building MSB P3-20B, Gainesville, FL, 32610, USA. asharma1@cop.ufl.edu.; Translational Drug Development Core, Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA. asharma1@cop.ufl.edu. |
| Source: | European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2025 May; Vol. 50 (3), pp. 205-218. Date of Electronic Publication: 2025 Mar 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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