The HDL-Mimetic Peptide 4F Mitigates Vascular and Cortical Amyloid Pathology and Associated Neuroinflammation in a Transgenic Mouse Model of Cerebral Amyloid Angiopathy and Alzheimer's Disease.

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Title: The HDL-Mimetic Peptide 4F Mitigates Vascular and Cortical Amyloid Pathology and Associated Neuroinflammation in a Transgenic Mouse Model of Cerebral Amyloid Angiopathy and Alzheimer's Disease.
Authors: Zhong R; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA., Chernick D; Graduate Program in Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA., Hottman D; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA., Tan Y; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA., Kim M; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA., Narayanan M; Graduate Program in Comparative and Molecular Biosciences, University of Minnesota, Minneapolis, MN, 55455, USA., Li L; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA. lil@umn.edu.; Graduate Program in Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA. lil@umn.edu.
Source: Molecular neurobiology [Mol Neurobiol] 2025 Aug; Vol. 62 (8), pp. 9507-9526. Date of Electronic Publication: 2025 Mar 22.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1559-1182
DOI:10.1007/s12035-025-04859-9