Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis.
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| Title: | Deletion of ENO1 sensitizes pancreatic cancer cells to gemcitabine via MYC/RRM1-mediated glycolysis. |
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| Authors: | Lu Y; Department of General Surgery, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, No. 77, Chang'an South Rd, Zhangjiagang, 215600, Jiangsu, China.; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, No.99, Huaihai West Rd, Xuzhou, 221006, Jiangsu, China., Ma H; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, No.99, Huaihai West Rd, Xuzhou, 221006, Jiangsu, China., Xiong X; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, No.99, Huaihai West Rd, Xuzhou, 221006, Jiangsu, China.; Department of General Surgery, The Affiliated Suqian Hospital of Xuzhou Medical University, No 138, Huanghe South Rd, Suqian, 223800, Jiangsu, China., Du Y; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, No.99, Huaihai West Rd, Xuzhou, 221006, Jiangsu, China., Liu L; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, No.99, Huaihai West Rd, Xuzhou, 221006, Jiangsu, China., Wang J; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, No.99, Huaihai West Rd, Xuzhou, 221006, Jiangsu, China. drwangji@gmail.com., Zhao W; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, No.99, Huaihai West Rd, Xuzhou, 221006, Jiangsu, China. wxzhaosurgy@163.com. |
| Source: | Scientific reports [Sci Rep] 2025 Mar 22; Vol. 15 (1), pp. 9941. Date of Electronic Publication: 2025 Mar 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-94319-0 |
