Evaluation of safety and efficacy of multiple intravenous and intraosseous doses of foetal liver-derived mesenchymal stem cells in children with severe osteogenesis imperfecta : the BOOST2B clinical trial protocol.
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| Title: | Evaluation of safety and efficacy of multiple intravenous and intraosseous doses of foetal liver-derived mesenchymal stem cells in children with severe osteogenesis imperfecta : the BOOST2B clinical trial protocol. |
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| Authors: | Madhuri V; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, (a unit of inStem, Bengaluru, Christian Medical College), Vellore, India.; Department of Orthopaedics, Amara Hospital, Tirupati, India., Ramesh S; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, (a unit of inStem, Bengaluru, Christian Medical College), Vellore, India., Goos A; Department of Clinical Science, Intervention & Technology, Karolinska Institutet, Stockholm, Sweden., Paul TV; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India., Nidugala Kesava S; Department of Radiology, Christian Medical College, Vellore, India., Mathews V; Department of Haematology, Christian Medical College, Vellore, India., Walther-Jallow L; Department of Clinical Science, Intervention & Technology, Karolinska Institutet, Stockholm, Sweden., Götherström C; Department of Clinical Science, Intervention & Technology, Karolinska Institutet, Stockholm, Sweden., Ekblad Å; Department of Clinical Science Intervention & Technology,, Karolinska Institutet, Stockholm, Sweden., Kumar V; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India., Ganesh S; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India., Loganathan L; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India., Raymond R; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India., Kumar A; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India., Daniel D; Department of Immunohematology and Transfusion Medicine, Christian Medical College, Vellore, India., Thomas N; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India., James D; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India., Kandagaddala M; Department of Radiology, Christian Medical College, Vellore, India., Mammen P; Department of Psychiatry, Christian Medical College, Vellore, India., B A; Department of Biostatistics, Christian Medical College, Vellore, India., Srivastava A; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India.; Department of Haematology, Christian Medical College, Vellore, India. |
| Corporate Authors: | BOOST2B Study Group |
| Source: | Bone & joint open [Bone Jt Open] 2025 Mar 24; Vol. 6 (3), pp. 361-372. Date of Electronic Publication: 2025 Mar 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: The British Editorial Society of Bone & Joint Surgery Country of Publication: England NLM ID: 101770336 Publication Model: Electronic Cited Medium: Internet ISSN: 2633-1462 (Electronic) Linking ISSN: 26331462 NLM ISO Abbreviation: Bone Jt Open Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40122106 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Evaluation of safety and efficacy of multiple intravenous and intraosseous doses of foetal liver-derived mesenchymal stem cells in children with severe osteogenesis imperfecta : the BOOST2B clinical trial protocol. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Madhuri+V%22">Madhuri V</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, (a unit of inStem, Bengaluru, Christian Medical College), Vellore, India.; Department of Orthopaedics, Amara Hospital, Tirupati, India.<br /><searchLink fieldCode="AU" term="%22Ramesh+S%22">Ramesh S</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, (a unit of inStem, Bengaluru, Christian Medical College), Vellore, India.<br /><searchLink fieldCode="AU" term="%22Goos+A%22">Goos A</searchLink>; Department of Clinical Science, Intervention & Technology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Paul+TV%22">Paul TV</searchLink>; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Nidugala+Kesava+S%22">Nidugala Kesava S</searchLink>; Department of Radiology, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Mathews+V%22">Mathews V</searchLink>; Department of Haematology, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Walther-Jallow+L%22">Walther-Jallow L</searchLink>; Department of Clinical Science, Intervention & Technology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Götherström+C%22">Götherström C</searchLink>; Department of Clinical Science, Intervention & Technology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ekblad+Å%22">Ekblad Å</searchLink>; Department of Clinical Science Intervention & Technology,, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Kumar+V%22">Kumar V</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Ganesh+S%22">Ganesh S</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Loganathan+L%22">Loganathan L</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Raymond+R%22">Raymond R</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Kumar+A%22">Kumar A</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Daniel+D%22">Daniel D</searchLink>; Department of Immunohematology and Transfusion Medicine, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Thomas+N%22">Thomas N</searchLink>; Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22James+D%22">James D</searchLink>; Department of Paediatric Orthopaedics, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Kandagaddala+M%22">Kandagaddala M</searchLink>; Department of Radiology, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Mammen+P%22">Mammen P</searchLink>; Department of Psychiatry, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22B+A%22">B A</searchLink>; Department of Biostatistics, Christian Medical College, Vellore, India.<br /><searchLink fieldCode="AU" term="%22Srivastava+A%22">Srivastava A</searchLink>; Center for Stem Cell Research, a unit of inStem, Bengaluru, Christian Medical College, Vellore, India.; Department of Haematology, Christian Medical College, Vellore, India. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22BOOST2B+Study+Group%22">BOOST2B Study Group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101770336%22">Bone & joint open</searchLink> [Bone Jt Open] 2025 Mar 24; Vol. 6 (3), pp. 361-372. <i>Date of Electronic Publication: </i>2025 Mar 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22The+British+Editorial+Society+of+Bone+%26+Joint+Surgery%22">The British Editorial Society of Bone & Joint Surgery </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101770336 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2633-1462 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226331462%22">26331462 </searchLink><i>NLM ISO Abbreviation: </i>Bone Jt Open <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40122106 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1302/2633-1462.63.BJO-2024-0115.R1 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 361 Titles: – TitleFull: Evaluation of safety and efficacy of multiple intravenous and intraosseous doses of foetal liver-derived mesenchymal stem cells in children with severe osteogenesis imperfecta : the BOOST2B clinical trial protocol. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Madhuri V – PersonEntity: Name: NameFull: Ramesh S – PersonEntity: Name: NameFull: Goos A – PersonEntity: Name: NameFull: Paul TV – PersonEntity: Name: NameFull: Nidugala Kesava S – PersonEntity: Name: NameFull: Mathews V – PersonEntity: Name: NameFull: Walther-Jallow L – PersonEntity: Name: NameFull: Götherström C – PersonEntity: Name: NameFull: Ekblad Å – PersonEntity: Name: NameFull: Kumar V – PersonEntity: Name: NameFull: Ganesh S – PersonEntity: Name: NameFull: Loganathan L – PersonEntity: Name: NameFull: Raymond R – PersonEntity: Name: NameFull: Kumar A – PersonEntity: Name: NameFull: Daniel D – PersonEntity: Name: NameFull: Thomas N – PersonEntity: Name: NameFull: James D – PersonEntity: Name: NameFull: Kandagaddala M – PersonEntity: Name: NameFull: Mammen P – PersonEntity: Name: NameFull: B A – PersonEntity: Name: NameFull: Srivastava A IsPartOfRelationships: – BibEntity: Dates: – D: 24 M: 03 Text: 2025 Mar 24 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2633-1462 Numbering: – Type: volume Value: 6 – Type: issue Value: 3 Titles: – TitleFull: Bone & joint open Type: main |
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