Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation.

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Title: Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation.
Authors: Park S; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Yoon K; Medpacto Inc., Seoul, Republic of Korea., Hong E; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Kim MW; Medpacto Inc., Seoul, Republic of Korea., Kang MG; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Mizuno S; Laboratory Animal Resource Center in Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Kim HJ; Medpacto Inc., Seoul, Republic of Korea., Lee MJ; Medpacto Inc., Seoul, Republic of Korea., Choi HJ; Medpacto Inc., Seoul, Republic of Korea., Heo JS; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Bae JB; Medpacto Inc., Seoul, Republic of Korea., An H; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Park N; Medpacto Inc., Seoul, Republic of Korea., Park H; GILO Institute, GILO Foundation, Seoul, Republic of Korea.; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea., Kim P; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Son M; GILO Institute, GILO Foundation, Seoul, Republic of Korea.; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea., Pang K; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Park JY; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Takahashi S; Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan., Kwon YJ; GILO Institute, GILO Foundation, Seoul, Republic of Korea., Kang DW; Medpacto Inc., Seoul, Republic of Korea., Kim SJ; GILO Institute, GILO Foundation, Seoul, Republic of Korea. jasonsjkim@gilo.or.kr.; Medpacto Inc., Seoul, Republic of Korea. jasonsjkim@gilo.or.kr.
Source: Bone research [Bone Res] 2025 Mar 24; Vol. 13 (1), pp. 40. Date of Electronic Publication: 2025 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: West China School of Stomatology, Sichuan University Country of Publication: China NLM ID: 101608652 Publication Model: Electronic Cited Medium: Print ISSN: 2095-4700 (Print) Linking ISSN: 20954700 NLM ISO Abbreviation: Bone Res Subsets: MEDLINE
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  Data: Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation.
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  Data: <searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+K%22">Yoon K</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hong+E%22">Hong E</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MW%22">Kim MW</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+MG%22">Kang MG</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Mizuno+S%22">Mizuno S</searchLink>; Laboratory Animal Resource Center in Transborder Medical Research Center, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MJ%22">Lee MJ</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+HJ%22">Choi HJ</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+JS%22">Heo JS</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+JB%22">Bae JB</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22An+H%22">An H</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+N%22">Park N</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+H%22">Park H</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+P%22">Kim P</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+M%22">Son M</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Pang+K%22">Pang K</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+JY%22">Park JY</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Takahashi+S%22">Takahashi S</searchLink>; Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Kwon+YJ%22">Kwon YJ</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+DW%22">Kang DW</searchLink>; Medpacto Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SJ%22">Kim SJ</searchLink>; GILO Institute, GILO Foundation, Seoul, Republic of Korea. jasonsjkim@gilo.or.kr.; Medpacto Inc., Seoul, Republic of Korea. jasonsjkim@gilo.or.kr.
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  Data: <searchLink fieldCode="JN" term="%22101608652%22">Bone research</searchLink> [Bone Res] 2025 Mar 24; Vol. 13 (1), pp. 40. <i>Date of Electronic Publication: </i>2025 Mar 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22West+China+School+of+Stomatology%2C+Sichuan+University%22">West China School of Stomatology, Sichuan University </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101608652 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2095-4700 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220954700%22">20954700 </searchLink><i>NLM ISO Abbreviation: </i>Bone Res <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41413-025-00419-y
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      – TitleFull: Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation.
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              Text: 2025 Mar 24
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