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The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19.

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Title: The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19.
Authors: Penrice-Randal R; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom., Bentley EG; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom., Sharma P; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom., Kirby A; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom., Donovan-Banfield I; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, England, United Kingdom., Kipar A; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom.; Laboratory for Animal Model Pathology, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland., Mega DF; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom., Bramwell C; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom.; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, England, United Kingdom., Sharp J; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, England, United Kingdom.; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, England, United Kingdom., Owen A; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, England, United Kingdom.; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, England, United Kingdom., Hiscox JA; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, England, United Kingdom.; A*STAR Infectious Diseases Laboratories (A*STAR ID Labs), Agency for Science, Technology and Research (A*STAR), , Singapore., Stewart JP; Department of Infection Biology and Microbiomes, University of Liverpool, Liverpool, England, United Kingdom.; Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, Liverpool, England, United Kingdom.
Source: Microbiology spectrum [Microbiol Spectr] 2025 May 06; Vol. 13 (5), pp. e0182924. Date of Electronic Publication: 2025 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE
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