CRISPR/Cas9-mediated deletion of a kinetoplast-associated gene attenuates virulence in Leishmania major parasites.

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Title: CRISPR/Cas9-mediated deletion of a kinetoplast-associated gene attenuates virulence in Leishmania major parasites.
Authors: Darzi F; Department of Parasitology, Pasteur Institute of Iran, 12 Farvardin St, Tehran, 1316943551, Iran., Khamesipour A; Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran., Tasbihi M; Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran., Bahraminasab M; Department of Biotechnology, Faculty of Sciences, University of Tehran, Tehran, Iran., Nateghi-Rostami M; Department of Parasitology, Pasteur Institute of Iran, 12 Farvardin St, Tehran, 1316943551, Iran. m_nateghi@pasteur.ac.ir.
Source: Medical microbiology and immunology [Med Microbiol Immunol] 2025 Mar 25; Vol. 214 (1), pp. 16. Date of Electronic Publication: 2025 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0314524 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1831 (Electronic) Linking ISSN: 03008584 NLM ISO Abbreviation: Med Microbiol Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1831
DOI:10.1007/s00430-025-00827-1