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Characterizing the tumor suppressor activity of FLCN in Birt-Hogg-Dubé syndrome cell models through transcriptomic and proteomic analysis.

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Title: Characterizing the tumor suppressor activity of FLCN in Birt-Hogg-Dubé syndrome cell models through transcriptomic and proteomic analysis.
Authors: Jones RA; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Dunlop EA; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Champion JD; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Doubleday PF; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.; Department of Biology, University of Vermont, Marsh Life Science 311, 109 Carrigan Drive, Burlington, VT, USA., Claessens T; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Jalali Z; Department of Biochemistry and Goodman Cancer Institute, McGill University, Montréal, QC, Canada., Seifan S; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Perry IA; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Giles P; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Harrison O; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Coull BJ; Lancaster Medical School, Lancaster University, Lancaster, LA1 4AT, UK., Houweling AC; Department of Human Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Pause A; Department of Biochemistry and Goodman Cancer Institute, McGill University, Montréal, QC, Canada., Ballif BA; Department of Biology, University of Vermont, Marsh Life Science 311, 109 Carrigan Drive, Burlington, VT, USA., Tee AR; Division of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK. teea@cardiff.ac.uk.
Source: Oncogene [Oncogene] 2025 Jun; Vol. 44 (23), pp. 1833-1843. Date of Electronic Publication: 2025 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
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