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Callus organoids reveal distinct cartilage to bone transition mechanisms across donors and a role for biological sex.

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Title: Callus organoids reveal distinct cartilage to bone transition mechanisms across donors and a role for biological sex.
Authors: Decoene I; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium., Svitina H; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium., Hamed MB; Laboratory of Molecular Bacteriology, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.; Molecular Biology Department, National Research Centre, 33 El Buhouth st, Dokii, 12622, Cairo, Egypt.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, VIB-KU Leuven Center for Brain & Disease Research, Herestraat, 3000, Leuven, Belgium., Economou A; Laboratory of Molecular Bacteriology, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000, Leuven, Belgium., Stegen S; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, Herestraat 49, 3000, Leuven, Belgium., Luyten FP; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium., Papantoniou I; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium. Ioannis.papantoniou@kuleuven.be.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium. Ioannis.papantoniou@kuleuven.be.; Institute for Chemical Engineering Sciences, Foundation for Research and Technology-Hellas (FORTH), Stadiou Street, Platani, box 1414, 26504, Patras, Greece. Ioannis.papantoniou@kuleuven.be.
Source: Bone research [Bone Res] 2025 Mar 26; Vol. 13 (1), pp. 41. Date of Electronic Publication: 2025 Mar 26.
Publication Type: Journal Article
Journal Info: Publisher: West China School of Stomatology, Sichuan University Country of Publication: China NLM ID: 101608652 Publication Model: Electronic Cited Medium: Print ISSN: 2095-4700 (Print) Linking ISSN: 20954700 NLM ISO Abbreviation: Bone Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Callus organoids reveal distinct cartilage to bone transition mechanisms across donors and a role for biological sex.
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  Data: <searchLink fieldCode="AU" term="%22Decoene+I%22">Decoene I</searchLink>; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Svitina+H%22">Svitina H</searchLink>; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Hamed+MB%22">Hamed MB</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.; Molecular Biology Department, National Research Centre, 33 El Buhouth st, Dokii, 12622, Cairo, Egypt.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, VIB-KU Leuven Center for Brain & Disease Research, Herestraat, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Economou+A%22">Economou A</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Stegen+S%22">Stegen S</searchLink>; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, Herestraat 49, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Luyten+FP%22">Luyten FP</searchLink>; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Papantoniou+I%22">Papantoniou I</searchLink>; Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium. Ioannis.papantoniou@kuleuven.be.; Prometheus Translational Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium. Ioannis.papantoniou@kuleuven.be.; Institute for Chemical Engineering Sciences, Foundation for Research and Technology-Hellas (FORTH), Stadiou Street, Platani, box 1414, 26504, Patras, Greece. Ioannis.papantoniou@kuleuven.be.
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  Data: <searchLink fieldCode="JN" term="%22101608652%22">Bone research</searchLink> [Bone Res] 2025 Mar 26; Vol. 13 (1), pp. 41. <i>Date of Electronic Publication: </i>2025 Mar 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22West+China+School+of+Stomatology%2C+Sichuan+University%22">West China School of Stomatology, Sichuan University </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101608652 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2095-4700 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220954700%22">20954700 </searchLink><i>NLM ISO Abbreviation: </i>Bone Res <i>Subsets: </i>MEDLINE
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              Text: 2025 Mar 26
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