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Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube.

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Title: Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube.
Authors: Beddows I; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Djirackor S; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Omran DK; Penn Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Jung E; Penn Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shih NN; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Roy R; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA., Hechmer A; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA., Olshen A; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA., Adelmant G; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Center for Emergent Drug Targets, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Tom A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Center for Emergent Drug Targets, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Morrison J; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Adams M; Genomics Core, Van Andel Research Institute, Grand Rapids, MI, USA., Rohrer DC; Pathology and Biorepository Core, Van Andel Research Institute, Grand Rapids, MI, USA., Schwartz LE; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pearce CL; Department of Epidemiology, University of Michigan School of Public Health and Rogel Cancer Center, Ann Arbor, MI, USA., Auman H; Canary Foundation, Palo Alto, CA, USA., Marto JA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Center for Emergent Drug Targets, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Drescher CW; Paul G. Allen Research Center, Swedish Cancer Institute, Seattle, WA, USA. cdresche@fredhutch.org.; Translational Research Program, Fred Hutchinson Cancer Center, Seattle, WA, USA. cdresche@fredhutch.org., Drapkin R; Penn Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. rdrapkin@pennmedicine.upenn.edu.; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA. rdrapkin@pennmedicine.upenn.edu., Shen H; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA. hui.shen@vai.org.
Source: Nature communications [Nat Commun] 2025 Mar 26; Vol. 16 (1), pp. 2981. Date of Electronic Publication: 2025 Mar 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube.
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  Data: <searchLink fieldCode="AU" term="%22Beddows+I%22">Beddows I</searchLink>; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Djirackor+S%22">Djirackor S</searchLink>; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Omran+DK%22">Omran DK</searchLink>; Penn Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Jung+E%22">Jung E</searchLink>; Penn Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shih+NN%22">Shih NN</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Roy+R%22">Roy R</searchLink>; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hechmer+A%22">Hechmer A</searchLink>; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Olshen+A%22">Olshen A</searchLink>; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Adelmant+G%22">Adelmant G</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Center for Emergent Drug Targets, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tom+A%22">Tom A</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Center for Emergent Drug Targets, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Morrison+J%22">Morrison J</searchLink>; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Adams+M%22">Adams M</searchLink>; Genomics Core, Van Andel Research Institute, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Rohrer+DC%22">Rohrer DC</searchLink>; Pathology and Biorepository Core, Van Andel Research Institute, Grand Rapids, MI, USA.<br /><searchLink fieldCode="AU" term="%22Schwartz+LE%22">Schwartz LE</searchLink>; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Pearce+CL%22">Pearce CL</searchLink>; Department of Epidemiology, University of Michigan School of Public Health and Rogel Cancer Center, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Auman+H%22">Auman H</searchLink>; Canary Foundation, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Marto+JA%22">Marto JA</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Blais Proteomics Center, Center for Emergent Drug Targets, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Drescher+CW%22">Drescher CW</searchLink>; Paul G. Allen Research Center, Swedish Cancer Institute, Seattle, WA, USA. cdresche@fredhutch.org.; Translational Research Program, Fred Hutchinson Cancer Center, Seattle, WA, USA. cdresche@fredhutch.org.<br /><searchLink fieldCode="AU" term="%22Drapkin+R%22">Drapkin R</searchLink>; Penn Ovarian Cancer Research Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. rdrapkin@pennmedicine.upenn.edu.; Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA. rdrapkin@pennmedicine.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Shen+H%22">Shen H</searchLink>; Department of Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA. hui.shen@vai.org.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Mar 26; Vol. 16 (1), pp. 2981. <i>Date of Electronic Publication: </i>2025 Mar 26.
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