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A phase 1 study of durvalumab as monotherapy or combined with tremelimumab with or without azacitidine in patients with myelodysplastic syndrome.

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Title: A phase 1 study of durvalumab as monotherapy or combined with tremelimumab with or without azacitidine in patients with myelodysplastic syndrome.
Authors: Garcia-Manero G; MD Anderson Cancer Center, Houston, TX, USA. ggarciam@mdanderson.org., Gaddh M; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Platzbecker U; University Hospital Leipzig, Leipzig, Germany., Lindsley RC; Dana-Farber Cancer Institute, Boston, MA, USA., Larson SM; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Chevassut T; Brighton and Sussex Medical School, University of Sussex, Brighton, UK., Fenaux P; Hôpital St Louis/Université Paris, Paris, France., Komrokji R; H Lee Moffitt Cancer Center, Tampa, FL, USA., Lyons R; Texas Oncology and US Oncology Research, San Antonio, TX, USA., Al-Kali A; Mayo Clinic, Rochester, MN, USA., Jiang Y; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals Research and Development, AstraZeneca, Gaithersburg, MD, USA., Bothos J; Oncology Research and Development, AstraZeneca, Gaithersburg, MD, USA., Townsley DM; Oncology Research and Development, AstraZeneca, Gaithersburg, MD, USA., Zeidan AM; Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Comprehensive Cancer Center, New Haven, CT, USA.
Source: Annals of hematology [Ann Hematol] 2025 Mar; Vol. 104 (3), pp. 1577-1585. Date of Electronic Publication: 2025 Mar 28.
Publication Type: Clinical Trial, Phase I; Comparative Study; Journal Article; Multicenter Study
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0584 (Electronic) Linking ISSN: 09395555 NLM ISO Abbreviation: Ann Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0584
DOI:10.1007/s00277-024-06081-4