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A phase 1 study of durvalumab as monotherapy or combined with tremelimumab with or without azacitidine in patients with myelodysplastic syndrome.

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Title: A phase 1 study of durvalumab as monotherapy or combined with tremelimumab with or without azacitidine in patients with myelodysplastic syndrome.
Authors: Garcia-Manero G; MD Anderson Cancer Center, Houston, TX, USA. ggarciam@mdanderson.org., Gaddh M; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Platzbecker U; University Hospital Leipzig, Leipzig, Germany., Lindsley RC; Dana-Farber Cancer Institute, Boston, MA, USA., Larson SM; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Chevassut T; Brighton and Sussex Medical School, University of Sussex, Brighton, UK., Fenaux P; Hôpital St Louis/Université Paris, Paris, France., Komrokji R; H Lee Moffitt Cancer Center, Tampa, FL, USA., Lyons R; Texas Oncology and US Oncology Research, San Antonio, TX, USA., Al-Kali A; Mayo Clinic, Rochester, MN, USA., Jiang Y; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals Research and Development, AstraZeneca, Gaithersburg, MD, USA., Bothos J; Oncology Research and Development, AstraZeneca, Gaithersburg, MD, USA., Townsley DM; Oncology Research and Development, AstraZeneca, Gaithersburg, MD, USA., Zeidan AM; Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Comprehensive Cancer Center, New Haven, CT, USA.
Source: Annals of hematology [Ann Hematol] 2025 Mar; Vol. 104 (3), pp. 1577-1585. Date of Electronic Publication: 2025 Mar 28.
Publication Type: Clinical Trial, Phase I; Comparative Study; Journal Article; Multicenter Study
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0584 (Electronic) Linking ISSN: 09395555 NLM ISO Abbreviation: Ann Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A phase 1 study of durvalumab as monotherapy or combined with tremelimumab with or without azacitidine in patients with myelodysplastic syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Garcia-Manero+G%22">Garcia-Manero G</searchLink>; MD Anderson Cancer Center, Houston, TX, USA. ggarciam@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Gaddh+M%22">Gaddh M</searchLink>; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Platzbecker+U%22">Platzbecker U</searchLink>; University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Lindsley+RC%22">Lindsley RC</searchLink>; Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Larson+SM%22">Larson SM</searchLink>; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chevassut+T%22">Chevassut T</searchLink>; Brighton and Sussex Medical School, University of Sussex, Brighton, UK.<br /><searchLink fieldCode="AU" term="%22Fenaux+P%22">Fenaux P</searchLink>; Hôpital St Louis/Université Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Komrokji+R%22">Komrokji R</searchLink>; H Lee Moffitt Cancer Center, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Lyons+R%22">Lyons R</searchLink>; Texas Oncology and US Oncology Research, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Al-Kali+A%22">Al-Kali A</searchLink>; Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals Research and Development, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bothos+J%22">Bothos J</searchLink>; Oncology Research and Development, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Townsley+DM%22">Townsley DM</searchLink>; Oncology Research and Development, AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zeidan+AM%22">Zeidan AM</searchLink>; Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Comprehensive Cancer Center, New Haven, CT, USA.
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  Data: <searchLink fieldCode="JN" term="%229107334%22">Annals of hematology</searchLink> [Ann Hematol] 2025 Mar; Vol. 104 (3), pp. 1577-1585. <i>Date of Electronic Publication: </i>2025 Mar 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9107334 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0584 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209395555%22">09395555 </searchLink><i>NLM ISO Abbreviation: </i>Ann Hematol <i>Subsets: </i>MEDLINE
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              Text: 2025 Mar
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