Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials.
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| Title: | Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials. |
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| Authors: | Cooper CL; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Morrow G; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Yuan M; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Postler TS; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Neal ML; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA., Cross RW; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., Woolsey C; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., Agans KN; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., Borisevich V; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., McNamara RP; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA., Atyeo C; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA., Roy V; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA., Germosen D; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA., Hou F; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Li SL; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Reiserova L; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Choi Y; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Wilson A; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Wagner D; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Wallace-Selman O; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Carpov A; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Geng F; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Frederick DJ; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., DeStefano J; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Ercolini AM; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Enriquez AS; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA 92037, USA., Hastie KM; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA 92037, USA., Ramos da Silva S; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Sayeed E; IAVI, New York, NY 10004, USA., Coleman JW; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA., Kilianski A; IAVI, New York, NY 10004, USA., Alter G; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA., Saphire EO; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA 92037, USA., Aitchison JD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA; Departments of Pediatrics and Biochemistry, University of Washington, Seattle, WA 98109, USA., Geisbert TW; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA., Gupta SB; IAVI, New York, NY 10004, USA., Feinberg MB; IAVI, New York, NY 10004, USA., Parks CL; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA. Electronic address: cparks@iavi.org. |
| Source: | EBioMedicine [EBioMedicine] 2025 Apr; Vol. 114, pp. 105647. Date of Electronic Publication: 2025 Mar 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40157130 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cooper+CL%22">Cooper CL</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Morrow+G%22">Morrow G</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+M%22">Yuan M</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Postler+TS%22">Postler TS</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Neal+ML%22">Neal ML</searchLink>; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Cross+RW%22">Cross RW</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Woolsey+C%22">Woolsey C</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Agans+KN%22">Agans KN</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Borisevich+V%22">Borisevich V</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22McNamara+RP%22">McNamara RP</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Atyeo+C%22">Atyeo C</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Roy+V%22">Roy V</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Germosen+D%22">Germosen D</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Hou+F%22">Hou F</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Li+SL%22">Li SL</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Reiserova+L%22">Reiserova L</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Choi+Y%22">Choi Y</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+A%22">Wilson A</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Wagner+D%22">Wagner D</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Wallace-Selman+O%22">Wallace-Selman O</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Carpov+A%22">Carpov A</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Geng+F%22">Geng F</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Frederick+DJ%22">Frederick DJ</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22DeStefano+J%22">DeStefano J</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Ercolini+AM%22">Ercolini AM</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Enriquez+AS%22">Enriquez AS</searchLink>; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Hastie+KM%22">Hastie KM</searchLink>; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Ramos+da+Silva+S%22">Ramos da Silva S</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Sayeed+E%22">Sayeed E</searchLink>; IAVI, New York, NY 10004, USA.<br /><searchLink fieldCode="AU" term="%22Coleman+JW%22">Coleman JW</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA.<br /><searchLink fieldCode="AU" term="%22Kilianski+A%22">Kilianski A</searchLink>; IAVI, New York, NY 10004, USA.<br /><searchLink fieldCode="AU" term="%22Alter+G%22">Alter G</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Saphire+EO%22">Saphire EO</searchLink>; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Aitchison+JD%22">Aitchison JD</searchLink>; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA; Departments of Pediatrics and Biochemistry, University of Washington, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Geisbert+TW%22">Geisbert TW</searchLink>; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+SB%22">Gupta SB</searchLink>; IAVI, New York, NY 10004, USA.<br /><searchLink fieldCode="AU" term="%22Feinberg+MB%22">Feinberg MB</searchLink>; IAVI, New York, NY 10004, USA.<br /><searchLink fieldCode="AU" term="%22Parks+CL%22">Parks CL</searchLink>; IAVI, Vaccine Design and Development Laboratory, Jersey City, NJ 07302, USA. Electronic address: cparks@iavi.org. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101647039%22">EBioMedicine</searchLink> [EBioMedicine] 2025 Apr; Vol. 114, pp. 105647. <i>Date of Electronic Publication: </i>2025 Mar 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101647039 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-3964 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223523964%22">23523964 </searchLink><i>NLM ISO Abbreviation: </i>EBioMedicine <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ebiom.2025.105647 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 105647 Titles: – TitleFull: Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cooper CL – PersonEntity: Name: NameFull: Morrow G – PersonEntity: Name: NameFull: Yuan M – PersonEntity: Name: NameFull: Postler TS – PersonEntity: Name: NameFull: Neal ML – PersonEntity: Name: NameFull: Cross RW – PersonEntity: Name: NameFull: Woolsey C – PersonEntity: Name: NameFull: Agans KN – PersonEntity: Name: NameFull: Borisevich V – PersonEntity: Name: NameFull: McNamara RP – PersonEntity: Name: NameFull: Atyeo C – PersonEntity: Name: NameFull: Roy V – PersonEntity: Name: NameFull: Germosen D – PersonEntity: Name: NameFull: Hou F – PersonEntity: Name: NameFull: Li SL – PersonEntity: Name: NameFull: Reiserova L – PersonEntity: Name: NameFull: Choi Y – PersonEntity: Name: NameFull: Wilson A – PersonEntity: Name: NameFull: Wagner D – PersonEntity: Name: NameFull: Wallace-Selman O – PersonEntity: Name: NameFull: Carpov A – PersonEntity: Name: NameFull: Geng F – PersonEntity: Name: NameFull: Frederick DJ – PersonEntity: Name: NameFull: DeStefano J – PersonEntity: Name: NameFull: Ercolini AM – PersonEntity: Name: NameFull: Enriquez AS – PersonEntity: Name: NameFull: Hastie KM – PersonEntity: Name: NameFull: Ramos da Silva S – PersonEntity: Name: NameFull: Sayeed E – PersonEntity: Name: NameFull: Coleman JW – PersonEntity: Name: NameFull: Kilianski A – PersonEntity: Name: NameFull: Alter G – PersonEntity: Name: NameFull: Saphire EO – PersonEntity: Name: NameFull: Aitchison JD – PersonEntity: Name: NameFull: Geisbert TW – PersonEntity: Name: NameFull: Gupta SB – PersonEntity: Name: NameFull: Feinberg MB – PersonEntity: Name: NameFull: Parks CL IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2025 Apr Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2352-3964 Numbering: – Type: volume Value: 114 Titles: – TitleFull: EBioMedicine Type: main |
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