An unusual phenotype of hereditary AApoAI amyloidosis caused by a novel Asp20Tyr substitution is linked to pH-dependent aggregation of apolipoprotein A-I.

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Bibliographic Details
Title: An unusual phenotype of hereditary AApoAI amyloidosis caused by a novel Asp20Tyr substitution is linked to pH-dependent aggregation of apolipoprotein A-I.
Authors: Prokaeva T; Amyloidosis Center, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA. Electronic address: prokaeva@bu.edu., Jayaraman S; Department of Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Klimtchuk E; Amyloidosis Center, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Burke N; Amyloidosis Center, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Spencer B; Amyloidosis Center, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Nedelkov D; Isoformix Inc., Sugar Land, TX, USA., Chen H; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Dasari S; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., McPhail ED; Department of Laboratory of Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Pereira L; Department of Hematology & Medical Oncology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Payne MC; Division of Gastroenterology, Department of Internal Medicine, Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, USA., Wong S; Amyloidosis Center, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Burks EJ; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Sanchorawala V; Amyloidosis Center, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA., Gursky O; Department of Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA. Electronic address: gursky@bu.edu.
Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Jun; Vol. 1871 (5), pp. 167820. Date of Electronic Publication: 2025 Mar 29.
Publication Type: Journal Article; Case Reports; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-260X
DOI:10.1016/j.bbadis.2025.167820