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Invigorating discovery and clinical translation of aging biomarkers.

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Title: Invigorating discovery and clinical translation of aging biomarkers.
Authors: Jacques E; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Herzog C; Biomarkers of Aging Consortium.; University of Innsbruck, Innsbruck, Austria.; University College London, London, UK., Ying K; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Biomarkers of Aging Consortium.; T. H. Chan School of Public Health, Harvard University, Boston, MA, USA., Tomusiak A; Buck Institute for Research on Aging, Novato, CA, USA., Kasamoto J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Sehgal R; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Paulson S; Methuselah Foundation., Reinhard J; Evotec SE., Träuble J; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK., Hastings WJ; Institute for Advancing Health Through Agriculture, Texas A&M University, College Station, TX, USA.; Department of Nutrition, Texas A&M University, College Station, TX, USA., Tyshkovskiy A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Hägg S; Biomarkers of Aging Consortium.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Earls JC; Buck Institute for Research on Aging, Novato, CA, USA., Behrens CE; Bayer Consumer Health., Lasky-Su J; Biomarkers of Aging Consortium.; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Zhou G; Regenerative Bio Inc, Hangzhou, China.; Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, China., Morgen E; BioAge Labs, Richmond, CA, USA., Tsang JS; Center for Systems and Engineering Immunology, Departments of Immunobiology and Biomedical Engineering, Yale University School of Medicine, New Haven, CT, USA.; Chan Zuckerberg Biohub New York, New Haven, CT, USA., Marioni RE; Biomarkers of Aging Consortium.; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Ma XJ; Alamar Biosciences, Inc, Fremont, CA, USA., Stolzing A; Loughborough University, Loughborough, UK., Glorioso C; NeuroAge Therapeutics., Gootenberg JS; Department of Medicine, Division of Engineering in Medicine Brigham and Women's Hospital Harvard Medical School, Boston, MA, USA.; Gene and Cell Therapy Institute Mass General Brigham, Cambridge, MA, USA.; Center for Virology and Vaccine Research Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA, USA., Abudayyeh OO; Gene and Cell Therapy Institute Mass General Brigham, Cambridge, MA, USA.; Center for Virology and Vaccine Research Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA, USA.; Department of Medicine Division of Engineering in Medicine Brigham and Women's Hospital Harvard Medical School, Boston, MA, USA., Argentieri MA; Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA., Mak RH; Department of Radiation Oncology, Dana-Farber/Brigham Cancer Center, Boston, MA, USA.; Mass General Brigham Artificial Intelligence in Medicine Program, Boston, MA, USA., Cox LS; Department of Biochemistry, University of Oxford, Oxford, UK.; Wellcome Leap Dynamic Resilience., Brack AS; Advanced Research Projects Agency for Health (ARPA-H)., Lauc G; Genos Glycoscience Research Laboratory, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia., Furman D; Biomarkers of Aging Consortium.; Buck Institute for Research on Aging, Novato, CA, USA.; Stanford 1000 Immunomes Project, Stanford University School of Medicine, Stanford, CA, USA., Buenrostro JD; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schumacher B; Institute for Genome Stability in Aging and Disease, University Hospital and University of Cologne, Cologne, Germany.; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., Justice JN; Biomarkers of Aging Consortium.; XPRIZE Foundation, Culver City, CA, USA.; Department of Internal Medicine - Gerontology and Geriatrics, Wake Forest School of Medicine, Winston-, Salem, NC, USA., Woods T; Collider Health.; International Institute of Longevity., Gobel D; Methuselah Foundation., Perez VI; Hevolution Foundation., Sinclair DA; Department of Genetics, Harvard Medical School, Boston, MA, USA., Maier AB; Biomarkers of Aging Consortium.; Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences, Vrije Universiteit, Amsterdam, Netherlands.; NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Barzilai N; Biomarkers of Aging Consortium.; Institute for Aging Research, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA., Snyder MP; Biomarkers of Aging Consortium.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Center for Genomics and Personalized Medicine, Stanford, CA, USA., Wyss-Coray T; Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.; The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA, USA., Horvath S; Biomarkers of Aging Consortium.; Altos Labs, Cambridge, UK., Ferrucci L; Biomarkers of Aging Consortium.; Intramural Research Program of the National Institute on Aging, NIH, Baltimore, MD, USA., Poganik JR; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. jpoganik@bwh.harvard.edu.; Biomarkers of Aging Consortium, . jpoganik@bwh.harvard.edu., Moqri M; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. mmoqri@bwh.harvard.edu.; Biomarkers of Aging Consortium, . mmoqri@bwh.harvard.edu.; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA. mmoqri@bwh.harvard.edu.; Department of Obstetrics and Gynecology, School of Medicine, Stanford University, Stanford, CA, USA. mmoqri@bwh.harvard.edu., Gladyshev VN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. vgladyshev@bwh.harvard.edu.; Biomarkers of Aging Consortium, . vgladyshev@bwh.harvard.edu.
Source: Nature aging [Nat Aging] 2025 Apr; Vol. 5 (4), pp. 539-543.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group US Country of Publication: United States NLM ID: 101773306 Publication Model: Print Cited Medium: Internet ISSN: 2662-8465 (Electronic) Linking ISSN: 26628465 NLM ISO Abbreviation: Nat Aging Subsets: MEDLINE; In Process
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