Neurological disability and brain grey matter atrophy in primary progressive multiple sclerosis are determined by microstructural lesional changes, but not by lesion load.

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Title: Neurological disability and brain grey matter atrophy in primary progressive multiple sclerosis are determined by microstructural lesional changes, but not by lesion load.
Authors: Ladopoulos T; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany. Theodoros.Ladopoulos@rub.de.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany. Theodoros.Ladopoulos@rub.de., Abbas Z; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Krieger B; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany., Bellenberg B; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany., James JC; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Bauer J; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Gold R; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Lukas C; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany., Schneider R; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany.
Source: Journal of neurology [J Neurol] 2025 Apr 01; Vol. 272 (4), pp. 302. Date of Electronic Publication: 2025 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Neurological disability and brain grey matter atrophy in primary progressive multiple sclerosis are determined by microstructural lesional changes, but not by lesion load.
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  Data: <searchLink fieldCode="AU" term="%22Ladopoulos+T%22">Ladopoulos T</searchLink>; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany. Theodoros.Ladopoulos@rub.de.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany. Theodoros.Ladopoulos@rub.de.<br /><searchLink fieldCode="AU" term="%22Abbas+Z%22">Abbas Z</searchLink>; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Krieger+B%22">Krieger B</searchLink>; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Bellenberg+B%22">Bellenberg B</searchLink>; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22James+JC%22">James JC</searchLink>; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+J%22">Bauer J</searchLink>; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Gold+R%22">Gold R</searchLink>; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Lukas+C%22">Lukas C</searchLink>; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+R%22">Schneider R</searchLink>; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany.
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  Data: <searchLink fieldCode="JN" term="%220423161%22">Journal of neurology</searchLink> [J Neurol] 2025 Apr 01; Vol. 272 (4), pp. 302. <i>Date of Electronic Publication: </i>2025 Apr 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0423161 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1459 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203405354%22">03405354 </searchLink><i>NLM ISO Abbreviation: </i>J Neurol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00415-025-13043-x
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        Text: English
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      – TitleFull: Neurological disability and brain grey matter atrophy in primary progressive multiple sclerosis are determined by microstructural lesional changes, but not by lesion load.
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              Text: 2025 Apr 01
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              Y: 2025
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