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PU.1/Spi1 exacerbates ischemia-reperfusion induced acute kidney injury via upregulating Gata2 and promoting fibroblast activation.

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Title: PU.1/Spi1 exacerbates ischemia-reperfusion induced acute kidney injury via upregulating Gata2 and promoting fibroblast activation.
Authors: Zong C; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China., Xu GL; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China., Ning M; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China., Li JY; Department of Nephrology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China., Wang X; Department of Nephrology, Children's Hospital of Fudan University, Shanghai, 201103, China., Guo HJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China., Zhang LH; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China., Zhou L; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China., Xu C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China., Yang ZH; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China., Lu LM; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. lulimin@shmu.edu.cn.; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China. lulimin@shmu.edu.cn., Niu JY; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China. njyphd2008@163.com.; Center of Community-based Health Research, Fudan University, Shanghai, 200240, China. njyphd2008@163.com.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2025 Aug; Vol. 46 (8), pp. 2251-2266. Date of Electronic Publication: 2025 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PU.1/Spi1 exacerbates ischemia-reperfusion induced acute kidney injury via upregulating Gata2 and promoting fibroblast activation.
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  Data: <searchLink fieldCode="AU" term="%22Zong+C%22">Zong C</searchLink>; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.<br /><searchLink fieldCode="AU" term="%22Xu+GL%22">Xu GL</searchLink>; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.<br /><searchLink fieldCode="AU" term="%22Ning+M%22">Ning M</searchLink>; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Li+JY%22">Li JY</searchLink>; Department of Nephrology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Nephrology, Children's Hospital of Fudan University, Shanghai, 201103, China.<br /><searchLink fieldCode="AU" term="%22Guo+HJ%22">Guo HJ</searchLink>; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Zhang+LH%22">Zhang LH</searchLink>; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.<br /><searchLink fieldCode="AU" term="%22Yang+ZH%22">Yang ZH</searchLink>; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.<br /><searchLink fieldCode="AU" term="%22Lu+LM%22">Lu LM</searchLink>; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. lulimin@shmu.edu.cn.; National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China. lulimin@shmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Niu+JY%22">Niu JY</searchLink>; Department of Nephrology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China. njyphd2008@163.com.; Center of Community-based Health Research, Fudan University, Shanghai, 200240, China. njyphd2008@163.com.
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  Data: <searchLink fieldCode="JN" term="%22100956087%22">Acta pharmacologica Sinica</searchLink> [Acta Pharmacol Sin] 2025 Aug; Vol. 46 (8), pp. 2251-2266. <i>Date of Electronic Publication: </i>2025 Apr 01.
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