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Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction.

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Title: Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction.
Authors: Wang H; Eli Lilly and Company, Indianapolis, Indiana, USA., Serap Monkul Nery E; Eli Lilly and Company, Indianapolis, Indiana, USA., Ardayfio P; Eli Lilly and Company, Indianapolis, Indiana, USA., Khanna R; Eli Lilly and Company, Indianapolis, Indiana, USA., Otero Svaldi D; Eli Lilly and Company, Indianapolis, Indiana, USA., Gueorguieva I; Eli Lilly and Company, Indianapolis, Indiana, USA., Shcherbinin S; Eli Lilly and Company, Indianapolis, Indiana, USA., Andersen SW; Eli Lilly and Company, Indianapolis, Indiana, USA., Hauck PM; Eli Lilly and Company, Indianapolis, Indiana, USA., Engle SE; Eli Lilly and Company, Indianapolis, Indiana, USA., Brooks DA; Eli Lilly and Company, Indianapolis, Indiana, USA., Collins EC; Eli Lilly and Company, Indianapolis, Indiana, USA., Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, and the UK Dementia Research Institute, UCL Queen Square Institute of Neurology, London, UK., Greenberg SM; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Salloway S; Butler Hospital, Providence, Rhode Island, USA.; Department of Neurology and Department of Psychiatry, Alpert Medical School of Brown University, Providence, Rhode Island, USA., Mintun MA; Eli Lilly and Company, Indianapolis, Indiana, USA., Sims JR; Eli Lilly and Company, Indianapolis, Indiana, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Apr; Vol. 21 (4), pp. e70062.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Modified titration of donanemab reduces ARIA risk and maintains amyloid reduction.
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  Data: <searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Serap+Monkul+Nery+E%22">Serap Monkul Nery E</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Ardayfio+P%22">Ardayfio P</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Khanna+R%22">Khanna R</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Otero+Svaldi+D%22">Otero Svaldi D</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Gueorguieva+I%22">Gueorguieva I</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Shcherbinin+S%22">Shcherbinin S</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Andersen+SW%22">Andersen SW</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Hauck+PM%22">Hauck PM</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Engle+SE%22">Engle SE</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Brooks+DA%22">Brooks DA</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Collins+EC%22">Collins EC</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Fox+NC%22">Fox NC</searchLink>; Dementia Research Centre, Department of Neurodegenerative Disease, and the UK Dementia Research Institute, UCL Queen Square Institute of Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Greenberg+SM%22">Greenberg SM</searchLink>; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Salloway+S%22">Salloway S</searchLink>; Butler Hospital, Providence, Rhode Island, USA.; Department of Neurology and Department of Psychiatry, Alpert Medical School of Brown University, Providence, Rhode Island, USA.<br /><searchLink fieldCode="AU" term="%22Mintun+MA%22">Mintun MA</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Sims+JR%22">Sims JR</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2025 Apr; Vol. 21 (4), pp. e70062.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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        Value: 10.1002/alz.70062
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              Text: 2025 Apr
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