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Serum type I interferon score as a disease activity biomarker in patients with diffuse cutaneous systemic sclerosis: a retrospective cohort study.

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Title: Serum type I interferon score as a disease activity biomarker in patients with diffuse cutaneous systemic sclerosis: a retrospective cohort study.
Authors: Hinchcliff M; Department of Internal Medicine, Section of Rheumatology, Allergy, and Immunology, Yale School of Medicine, New Haven, CT, USA. Electronic address: Monique.hinchcliff@yale.edu., Khanna D; Division of Rheumatology, Scleroderma Program, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., De Lorenzis E; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Division of Rheumatology, Catholic University of the Sacred Heart, Largo Francesco Vito 1, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy., Di Donato S; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK., Carriero A; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK., Ross RL; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK., Huang S; Division of Rheumatology, Scleroderma Program, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Biostatistics, University of Michigan School of Public Health, University of Michigan, Ann Arbor, MI, USA., Aren KA; Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Bernstein EJ; Division of Rheumatology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Carns M; Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Castelino FV; Division of Rheumatology, Massachusetts General Hospital, Boston, MA, USA., Domsic RT; Division of Rheumatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Frech TM; Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Tennessee Valley Health Care System, Nashville, TN, USA., Gordon JK; Department of Rheumatology, Hospital for Special Surgery, New York, NY, USA., Hant FN; Division of Rheumatology, Medical University of South Carolina, Charleston, SC, USA., Shah AA; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Shanmugam VK; Division of Rheumatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Steen VD; Division of Rheumatology, Georgetown Medical Center, Washington DC, USA., Assassi S; Division of Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, USA., Del Galdo F; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine and Biomedical Research Centre, Chapel Allerton Hospital, Leeds, UK. Electronic address: f.delgaldo@leeds.ac.uk.
Source: The Lancet. Rheumatology [Lancet Rheumatol] 2025 Jun; Vol. 7 (6), pp. e403-e414. Date of Electronic Publication: 2025 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101765308 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2665-9913 (Electronic) Linking ISSN: 26659913 NLM ISO Abbreviation: Lancet Rheumatol Subsets: MEDLINE
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  Data: Serum type I interferon score as a disease activity biomarker in patients with diffuse cutaneous systemic sclerosis: a retrospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Hinchcliff+M%22">Hinchcliff M</searchLink>; Department of Internal Medicine, Section of Rheumatology, Allergy, and Immunology, Yale School of Medicine, New Haven, CT, USA. Electronic address: Monique.hinchcliff@yale.edu.<br /><searchLink fieldCode="AU" term="%22Khanna+D%22">Khanna D</searchLink>; Division of Rheumatology, Scleroderma Program, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22De+Lorenzis+E%22">De Lorenzis E</searchLink>; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Division of Rheumatology, Catholic University of the Sacred Heart, Largo Francesco Vito 1, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Donato+S%22">Di Donato S</searchLink>; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Carriero+A%22">Carriero A</searchLink>; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Ross+RL%22">Ross RL</searchLink>; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Huang+S%22">Huang S</searchLink>; Division of Rheumatology, Scleroderma Program, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Biostatistics, University of Michigan School of Public Health, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Aren+KA%22">Aren KA</searchLink>; Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bernstein+EJ%22">Bernstein EJ</searchLink>; Division of Rheumatology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Carns+M%22">Carns M</searchLink>; Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Castelino+FV%22">Castelino FV</searchLink>; Division of Rheumatology, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Domsic+RT%22">Domsic RT</searchLink>; Division of Rheumatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Frech+TM%22">Frech TM</searchLink>; Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Tennessee Valley Health Care System, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+JK%22">Gordon JK</searchLink>; Department of Rheumatology, Hospital for Special Surgery, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hant+FN%22">Hant FN</searchLink>; Division of Rheumatology, Medical University of South Carolina, Charleston, SC, USA.<br /><searchLink fieldCode="AU" term="%22Shah+AA%22">Shah AA</searchLink>; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shanmugam+VK%22">Shanmugam VK</searchLink>; Division of Rheumatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Steen+VD%22">Steen VD</searchLink>; Division of Rheumatology, Georgetown Medical Center, Washington DC, USA.<br /><searchLink fieldCode="AU" term="%22Assassi+S%22">Assassi S</searchLink>; Division of Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Del+Galdo+F%22">Del Galdo F</searchLink>; Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine and Biomedical Research Centre, Chapel Allerton Hospital, Leeds, UK. Electronic address: f.delgaldo@leeds.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101765308%22">The Lancet. Rheumatology</searchLink> [Lancet Rheumatol] 2025 Jun; Vol. 7 (6), pp. e403-e414. <i>Date of Electronic Publication: </i>2025 Mar 31.
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