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Application of cytochrome P450 enzyme assays to predict p53 inducers and AChE inhibitors that require metabolic activation.

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Title: Application of cytochrome P450 enzyme assays to predict p53 inducers and AChE inhibitors that require metabolic activation.
Authors: Ngan DK; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA., Sakamuru S; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA., Zhao J; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA., Xia M; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA., Ferguson SS; Division of Translational Toxicology, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, NC, USA., Reif DM; Division of Translational Toxicology, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, NC, USA., Simeonov A; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA., Huang R; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA. Electronic address: huangru@mail.nih.gov.
Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2025 Jun; Vol. 499, pp. 117315. Date of Electronic Publication: 2025 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Application of cytochrome P450 enzyme assays to predict p53 inducers and AChE inhibitors that require metabolic activation.
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  Data: <searchLink fieldCode="AU" term="%22Ngan+DK%22">Ngan DK</searchLink>; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Sakamuru+S%22">Sakamuru S</searchLink>; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Xia+M%22">Xia M</searchLink>; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Ferguson+SS%22">Ferguson SS</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Reif+DM%22">Reif DM</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Simeonov+A%22">Simeonov A</searchLink>; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Huang+R%22">Huang R</searchLink>; Division of Pre-clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Rockville, MD 20850, USA. Electronic address: huangru@mail.nih.gov.
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  Data: <searchLink fieldCode="JN" term="%220416575%22">Toxicology and applied pharmacology</searchLink> [Toxicol Appl Pharmacol] 2025 Jun; Vol. 499, pp. 117315. <i>Date of Electronic Publication: </i>2025 Apr 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0416575 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-0333 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220041008X%22">0041008X </searchLink><i>NLM ISO Abbreviation: </i>Toxicol Appl Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.taap.2025.117315
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        Text: English
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      – TitleFull: Application of cytochrome P450 enzyme assays to predict p53 inducers and AChE inhibitors that require metabolic activation.
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              Text: 2025 Jun
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              Y: 2025
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