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Nanocarrier Drug Release and Blood-Brain Barrier Penetration at Post-Stroke Microthrombi Monitored by Real-Time Förster Resonance Energy Transfer.

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Title: Nanocarrier Drug Release and Blood-Brain Barrier Penetration at Post-Stroke Microthrombi Monitored by Real-Time Förster Resonance Energy Transfer.
Authors: Khalin I; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich 81377, Germany.; Normandie University, UNICAEN, INSERM UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Institute Blood and Brain @ Caen-Normandie (BB@C), Caen 14000, France., Adarsh N; Laboratory de Biophotonique et Pharmacologie, University of Strasbourg, Strasbourg 60024, France.; Department of Polymer Chemistry, Government College Attingal, Thiruvananthapuram 695101, Kerala, India., Schifferer M; German Center for Neurodegenerative Diseases (DZNE), Munich 81377, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany., Wehn A; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich 81377, Germany.; Department of Neurosurgery, LMU University Hospital, Munich 81377, Germany., Boide-Trujillo VJ; Laboratory de Biophotonique et Pharmacologie, University of Strasbourg, Strasbourg 60024, France., Mamrak U; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich 81377, Germany., Shrouder J; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich 81377, Germany., Misgeld T; German Center for Neurodegenerative Diseases (DZNE), Munich 81377, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany.; Institute of Neuronal Cell Biology, Technical University of Munich, Munich 80802, Germany., Filser S; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich 81377, Germany.; Core Research Facilities and Services-Light Microscope Facility, German Center for Neurodegenerative Diseases (DZNE), Bonn 53127, Germany., Klymchenko AS; Laboratory de Biophotonique et Pharmacologie, University of Strasbourg, Strasbourg 60024, France., Plesnila N; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich 81377, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich 81377, Germany.
Source: ACS nano [ACS Nano] 2025 Apr 22; Vol. 19 (15), pp. 14780-14794. Date of Electronic Publication: 2025 Apr 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1936-086X
DOI:10.1021/acsnano.4c17011