A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer.

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Title: A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer.
Authors: Huang Z; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Mandelkow T; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Debatin NF; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Lurati MCJ; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ebner J; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Raedler JB; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; College of Arts and Sciences, Boston University, Boston, MA, USA., Bady E; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Müller JH; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Simon R; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Vettorazzi E; Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Menz A; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Möller K; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Gorbokon N; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sauter G; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Lennartz M; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Luebke AM; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Höflmayer D; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Krech T; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Clinical Center Osnabrück, Osnabrück, Germany., Lebok P; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Clinical Center Osnabrück, Osnabrück, Germany., Fraune C; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Clinical Center Osnabrück, Osnabrück, Germany., Hinsch A; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Jacobsen F; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Marx AH; Institute of Pathology, Klinikum Fürth, Fürth, Germany., Steurer S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Minner S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Dum D; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Weidemann S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bernreuther C; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Clauditz TS; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Burandt E; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Blessin NC; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Arnold-Heller-Straße 3, University Medical Center Schleswig-Holstein, Kiel, Germany.
Source: The Journal of pathology [J Pathol] 2025 Jun; Vol. 266 (2), pp. 192-203. Date of Electronic Publication: 2025 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE
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  Data: A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Huang+Z%22">Huang Z</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mandelkow+T%22">Mandelkow T</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Debatin+NF%22">Debatin NF</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lurati+MCJ%22">Lurati MCJ</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ebner+J%22">Ebner J</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Raedler+JB%22">Raedler JB</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; College of Arts and Sciences, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bady+E%22">Bady E</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+JH%22">Müller JH</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Simon+R%22">Simon R</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Vettorazzi+E%22">Vettorazzi E</searchLink>; Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Menz+A%22">Menz A</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Möller+K%22">Möller K</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gorbokon+N%22">Gorbokon N</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sauter+G%22">Sauter G</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lennartz+M%22">Lennartz M</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Luebke+AM%22">Luebke AM</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Höflmayer+D%22">Höflmayer D</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Krech+T%22">Krech T</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Clinical Center Osnabrück, Osnabrück, Germany.<br /><searchLink fieldCode="AU" term="%22Lebok+P%22">Lebok P</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Clinical Center Osnabrück, Osnabrück, Germany.<br /><searchLink fieldCode="AU" term="%22Fraune+C%22">Fraune C</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Clinical Center Osnabrück, Osnabrück, Germany.<br /><searchLink fieldCode="AU" term="%22Hinsch+A%22">Hinsch A</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jacobsen+F%22">Jacobsen F</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Marx+AH%22">Marx AH</searchLink>; Institute of Pathology, Klinikum Fürth, Fürth, Germany.<br /><searchLink fieldCode="AU" term="%22Steurer+S%22">Steurer S</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Minner+S%22">Minner S</searchLink>; 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Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Institute of Pathology, Arnold-Heller-Straße 3, University Medical Center Schleswig-Holstein, Kiel, Germany.
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