The effect of M-current activation on controller gain and obstructive sleep apnoea severity: a randomised controlled trial using flupirtine.
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| Title: | The effect of M-current activation on controller gain and obstructive sleep apnoea severity: a randomised controlled trial using flupirtine. |
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| Authors: | Thomson LDJ; Department of Physiology, School of Biomedical Sciences and Biomedical Discovery Institute, Monash University, Melbourne, VIC, Australia., Landry SA; Department of Physiology, School of Biomedical Sciences and Biomedical Discovery Institute, Monash University, Melbourne, VIC, Australia.; School of Psychological Science, Monash University, Melbourne, VIC, Australia., Arellano A; Department of Physiology, School of Biomedical Sciences and Biomedical Discovery Institute, Monash University, Melbourne, VIC, Australia., Collet J; Department of Physiology, School of Biomedical Sciences and Biomedical Discovery Institute, Monash University, Melbourne, VIC, Australia., Huddle S; Department of Respiratory and Sleep Medicine, Eastern Health, Melbourne, Australia., O'Driscoll DM; Department of Respiratory and Sleep Medicine, Eastern Health, Melbourne, Australia.; Eastern Health Clinical School, Monash University, Melbourne, VIC, Australia., Mann DL; School of Electrical Engineering and Computer Science, The University of Queensland, Brisbane, QLD, Australia., Beatty C; Department of Physiology, School of Biomedical Sciences and Biomedical Discovery Institute, Monash University, Melbourne, VIC, Australia., Joosten SA; School of Clinical Sciences, Monash University, Melbourne, VIC, Australia.; Monash Lung, Sleep, Allergy and Immunology, Monash Health, Clayton, VIC, Australia., Hamilton GS; School of Clinical Sciences, Monash University, Melbourne, VIC, Australia.; Monash Lung, Sleep, Allergy and Immunology, Monash Health, Clayton, VIC, Australia., Berger PJ; Hudson Institute of Medical Research, Clayton, VIC, Australia., Cooke I; Department of Physiology, School of Biomedical Sciences and Biomedical Discovery Institute, Monash University, Melbourne, VIC, Australia., Edwards BA; Department of Physiology, School of Biomedical Sciences and Biomedical Discovery Institute, Monash University, Melbourne, VIC, Australia.; School of Psychological Science, Monash University, Melbourne, VIC, Australia. |
| Source: | The Journal of physiology [J Physiol] 2025 May; Vol. 603 (10), pp. 3245-3260. Date of Electronic Publication: 2025 Apr 03. |
| Publication Type: | Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-7793 |
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| DOI: | 10.1113/JP288337 |
