Opioids diminish the placebo antidepressant response: Observational post hoc findings from a randomized controlled ketamine trial.

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Title: Opioids diminish the placebo antidepressant response: Observational post hoc findings from a randomized controlled ketamine trial.
Authors: Lii TR; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Flohr JR; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Okada RL; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA., Cianfichi LJ; Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA., Hack LM; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; Sierra Pacific Mental Illness Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA., Schatzberg AF; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA., Heifets BD; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: bheifets@stanford.edu.
Source: Journal of affective disorders [J Affect Disord] 2025 Jul 15; Vol. 381, pp. 200-204. Date of Electronic Publication: 2025 Apr 02.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lii+TR%22">Lii TR</searchLink>; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Flohr+JR%22">Flohr JR</searchLink>; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Okada+RL%22">Okada RL</searchLink>; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cianfichi+LJ%22">Cianfichi LJ</searchLink>; Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hack+LM%22">Hack LM</searchLink>; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA; Sierra Pacific Mental Illness Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schatzberg+AF%22">Schatzberg AF</searchLink>; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Heifets+BD%22">Heifets BD</searchLink>; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: bheifets@stanford.edu.
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  Data: <searchLink fieldCode="JN" term="%227906073%22">Journal of affective disorders</searchLink> [J Affect Disord] 2025 Jul 15; Vol. 381, pp. 200-204. <i>Date of Electronic Publication: </i>2025 Apr 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2FNorth-Holland+Biomedical+Press%22">Elsevier/North-Holland Biomedical Press </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7906073 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-2517 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201650327%22">01650327 </searchLink><i>NLM ISO Abbreviation: </i>J Affect Disord <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jad.2025.04.008
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        Text: English
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      – TitleFull: Opioids diminish the placebo antidepressant response: Observational post hoc findings from a randomized controlled ketamine trial.
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              Text: 2025 Jul 15
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