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A scaffold repositioning approach: dihydroBenzoImidazoTriazineDione (BITD) derivatives as selective ALDH1A1 inhibitors.

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Title: A scaffold repositioning approach: dihydroBenzoImidazoTriazineDione (BITD) derivatives as selective ALDH1A1 inhibitors.
Authors: Bernardoni BL; Department of Pharmacy, University of Pisa, 56126, Pisa, Italy., D'Agostino I; Department of Pharmacy, University of Pisa, 56126, Pisa, Italy. ilaria.dagostino@unipi.it., Siragusa S; Department of Pharmaceutical Sciences, University of Piemonte Orientale, 28100, Novara, Italy., Mori M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100, Siena, Italy., Garavaglia S; Department of Pharmaceutical Sciences, University of Piemonte Orientale, 28100, Novara, Italy. silvia.garavaglia@uniupo.it., La Motta C; Department of Pharmacy, University of Pisa, 56126, Pisa, Italy.
Source: Molecular diversity [Mol Divers] 2026 Feb; Vol. 30 (1), pp. 495-508. Date of Electronic Publication: 2025 Apr 04.
Publication Type: Journal Article
Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A scaffold repositioning approach: dihydroBenzoImidazoTriazineDione (BITD) derivatives as selective ALDH1A1 inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Bernardoni+BL%22">Bernardoni BL</searchLink>; Department of Pharmacy, University of Pisa, 56126, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22D'Agostino+I%22">D'Agostino I</searchLink>; Department of Pharmacy, University of Pisa, 56126, Pisa, Italy. ilaria.dagostino@unipi.it.<br /><searchLink fieldCode="AU" term="%22Siragusa+S%22">Siragusa S</searchLink>; Department of Pharmaceutical Sciences, University of Piemonte Orientale, 28100, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Mori+M%22">Mori M</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Garavaglia+S%22">Garavaglia S</searchLink>; Department of Pharmaceutical Sciences, University of Piemonte Orientale, 28100, Novara, Italy. silvia.garavaglia@uniupo.it.<br /><searchLink fieldCode="AU" term="%22La+Motta+C%22">La Motta C</searchLink>; Department of Pharmacy, University of Pisa, 56126, Pisa, Italy.
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  Data: <searchLink fieldCode="JN" term="%229516534%22">Molecular diversity</searchLink> [Mol Divers] 2026 Feb; Vol. 30 (1), pp. 495-508. <i>Date of Electronic Publication: </i>2025 Apr 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22ESCOM+Science+Publishers%22">ESCOM Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9516534 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-501X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213811991%22">13811991 </searchLink><i>NLM ISO Abbreviation: </i>Mol Divers <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s11030-025-11179-6
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              Text: 2026 Feb
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