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Inhibition of DNA polymerase eta-mediated translesion DNA synthesis with small molecule sensitises ovarian cancer stem-like cells to chemotherapy.

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Title: Inhibition of DNA polymerase eta-mediated translesion DNA synthesis with small molecule sensitises ovarian cancer stem-like cells to chemotherapy.
Authors: Bose S; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Saha P; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India., Alam MT; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India., Chatterjee B; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India., Sarkar M; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India., Dixit AK; Department of Biochemistry, Central Ayurveda Research Institute, Kolkata, India., Kumar D; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India., Pathak RK; Department of Chemical Science, Indian Institute of Science Education and Research Berhampur, Odisha, India., Tripathi PP; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India., Srivastava AK; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Source: British journal of pharmacology [Br J Pharmacol] 2025 Aug; Vol. 182 (15), pp. 3594-3611. Date of Electronic Publication: 2025 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of DNA polymerase eta-mediated translesion DNA synthesis with small molecule sensitises ovarian cancer stem-like cells to chemotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Bose+S%22">Bose S</searchLink>; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.<br /><searchLink fieldCode="AU" term="%22Saha+P%22">Saha P</searchLink>; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Alam+MT%22">Alam MT</searchLink>; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Chatterjee+B%22">Chatterjee B</searchLink>; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.<br /><searchLink fieldCode="AU" term="%22Sarkar+M%22">Sarkar M</searchLink>; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Dixit+AK%22">Dixit AK</searchLink>; Department of Biochemistry, Central Ayurveda Research Institute, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Kumar+D%22">Kumar D</searchLink>; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Pathak+RK%22">Pathak RK</searchLink>; Department of Chemical Science, Indian Institute of Science Education and Research Berhampur, Odisha, India.<br /><searchLink fieldCode="AU" term="%22Tripathi+PP%22">Tripathi PP</searchLink>; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.<br /><searchLink fieldCode="AU" term="%22Srivastava+AK%22">Srivastava AK</searchLink>; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
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  Data: <searchLink fieldCode="JN" term="%227502536%22">British journal of pharmacology</searchLink> [Br J Pharmacol] 2025 Aug; Vol. 182 (15), pp. 3594-3611. <i>Date of Electronic Publication: </i>2025 Apr 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7502536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5381 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071188%22">00071188 </searchLink><i>NLM ISO Abbreviation: </i>Br J Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1111/bph.70037
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        Text: English
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      – TitleFull: Inhibition of DNA polymerase eta-mediated translesion DNA synthesis with small molecule sensitises ovarian cancer stem-like cells to chemotherapy.
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              Text: 2025 Aug
              Type: published
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