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Two distinct cytokine response clusters identified in healthcare workers with apparent resistance to infection with Mycobacterium tuberculosis despite sustained occupational exposure.

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Title: Two distinct cytokine response clusters identified in healthcare workers with apparent resistance to infection with Mycobacterium tuberculosis despite sustained occupational exposure.
Authors: Balfour A; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Masina N; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Queiroz ATL; Laboratory of Clinical and Translational Research, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.; Multinational Organization Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Bahia, Brazil., Andrade BB; Laboratory of Clinical and Translational Research, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.; Multinational Organization Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Bahia, Brazil.; Instituto de Pesquisa Clínica e Translacional, Faculdade Zarns, Clariens Educação, Salvador, Bahia, Brazil., Fukutani ER; Laboratory of Clinical and Translational Research, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.; Multinational Organization Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Bahia, Brazil., Bekiswa A; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Lewinsohn D; Department of Medicine, Oregon Health and Science University, Portland, Oregon, USA.; Portland VA Medical Center, Portland, Oregon, USA., Lewinsohn D; Department of Pediatrics, Oregon Health and Science University, Portland, Oregon, USA., Goliath R; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Wilkinson KA; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; The Francis Crick Institute, London NW1 1 AT, UK., Schutz C; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Meintjes G; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK., Shey MS; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 28. Date of Electronic Publication: 2025 Mar 28.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Two distinct cytokine response clusters identified in healthcare workers with apparent resistance to infection with Mycobacterium tuberculosis despite sustained occupational exposure.
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  Data: <searchLink fieldCode="AU" term="%22Balfour+A%22">Balfour A</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Masina+N%22">Masina N</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Queiroz+ATL%22">Queiroz ATL</searchLink>; Laboratory of Clinical and Translational Research, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.; Multinational Organization Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Bahia, Brazil.<br /><searchLink fieldCode="AU" term="%22Andrade+BB%22">Andrade BB</searchLink>; Laboratory of Clinical and Translational Research, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.; Multinational Organization Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Bahia, Brazil.; Instituto de Pesquisa Clínica e Translacional, Faculdade Zarns, Clariens Educação, Salvador, Bahia, Brazil.<br /><searchLink fieldCode="AU" term="%22Fukutani+ER%22">Fukutani ER</searchLink>; Laboratory of Clinical and Translational Research, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.; Multinational Organization Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Bahia, Brazil.<br /><searchLink fieldCode="AU" term="%22Bekiswa+A%22">Bekiswa A</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Lewinsohn+D%22">Lewinsohn D</searchLink>; Department of Medicine, Oregon Health and Science University, Portland, Oregon, USA.; Portland VA Medical Center, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Lewinsohn+D%22">Lewinsohn D</searchLink>; Department of Pediatrics, Oregon Health and Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Goliath+R%22">Goliath R</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Wilkinson+KA%22">Wilkinson KA</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; The Francis Crick Institute, London NW1 1 AT, UK.<br /><searchLink fieldCode="AU" term="%22Schutz+C%22">Schutz C</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Meintjes+G%22">Meintjes G</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Shey+MS%22">Shey MS</searchLink>; Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
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