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ACT001 improves OVX-induced osteoporosis by suppressing the NF-κB/NLRP3 signaling pathway.

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Title: ACT001 improves OVX-induced osteoporosis by suppressing the NF-κB/NLRP3 signaling pathway.
Authors: Li Y; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China., Yang JY; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China., Lin ML; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China., Liu TZ; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China., Lu WN; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China., Yang Y; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China., Liu ZC; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China., Li JH; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China. lijianheng@hbu.edu.cn., Zhang GQ; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China. gqzhang@hbu.edu.cn., Guo JS; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China. jshguo@hbu.edu.cn.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2025 Apr 07; Vol. 31 (1), pp. 131. Date of Electronic Publication: 2025 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ACT001 improves OVX-induced osteoporosis by suppressing the NF-κB/NLRP3 signaling pathway.
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  Data: <searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.<br /><searchLink fieldCode="AU" term="%22Yang+JY%22">Yang JY</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.<br /><searchLink fieldCode="AU" term="%22Lin+ML%22">Lin ML</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.<br /><searchLink fieldCode="AU" term="%22Liu+TZ%22">Liu TZ</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.<br /><searchLink fieldCode="AU" term="%22Lu+WN%22">Lu WN</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.<br /><searchLink fieldCode="AU" term="%22Liu+ZC%22">Liu ZC</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China.<br /><searchLink fieldCode="AU" term="%22Li+JH%22">Li JH</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China. lijianheng@hbu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+GQ%22">Zhang GQ</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China. gqzhang@hbu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Guo+JS%22">Guo JS</searchLink>; State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, China. jshguo@hbu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229501023%22">Molecular medicine (Cambridge, Mass.)</searchLink> [Mol Med] 2025 Apr 07; Vol. 31 (1), pp. 131. <i>Date of Electronic Publication: </i>2025 Apr 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9501023 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-3658 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210761551%22">10761551 </searchLink><i>NLM ISO Abbreviation: </i>Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s10020-025-01189-3
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            – D: 07
              M: 04
              Text: 2025 Apr 07
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