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Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.

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Title: Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.
Authors: Nanamatsu A; Department of Medicine, Division of Nephrology and Hypertension., Rhodes GJ; Department of Medicine, Division of Nephrology and Hypertension., LaFavers KA; Department of Anatomy, Cell Biology and Physiology, Medicine., Micanovic R; Department of Medicine, Division of Nephrology and Hypertension., Lazar V; Department of Medicine, Division of Nephrology and Hypertension., Khan S; Department of Medicine, Division of Nephrology and Hypertension., Barwinska D; Department of Medicine, Division of Nephrology and Hypertension., Makino S; Department of Medicine, Division of Nephrology and Hypertension., Zollman A; Department of Medicine, Division of Nephrology and Hypertension., Cheng YH; Department of Medicine, Division of Nephrology and Hypertension., Doud EH; Department of Biochemistry and Molecular Biology.; Center for Proteome Analysis., Mosley AL; Department of Biochemistry and Molecular Biology.; Center for Proteome Analysis.; Center for Computational Biology and Bioinformatics., Repass MJ; Cellular Response Technologies Core, and., Kamocka MM; Department of Medicine, Division of Nephrology and Hypertension., Baride A; Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Phillips CL; Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Kelly KJ; Department of Medicine, Division of Nephrology and Hypertension.; Indianapolis Roudebush VA Medical Center, Indianapolis, Indiana, USA., Eadon MT; Department of Medicine, Division of Nephrology and Hypertension., Himmelfarb J; Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA., Kretzler M; Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA., Bacallao RL; Department of Medicine, Division of Nephrology and Hypertension., Dagher PC; Department of Medicine, Division of Nephrology and Hypertension., Hato T; Department of Medicine, Division of Nephrology and Hypertension.; Indianapolis Roudebush VA Medical Center, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., El-Achkar TM; Department of Medicine, Division of Nephrology and Hypertension.; Department of Anatomy, Cell Biology and Physiology, Medicine.; Indianapolis Roudebush VA Medical Center, Indianapolis, Indiana, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Apr 08; Vol. 135 (12). Date of Electronic Publication: 2025 Apr 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.
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  Data: <searchLink fieldCode="AU" term="%22Nanamatsu+A%22">Nanamatsu A</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Rhodes+GJ%22">Rhodes GJ</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22LaFavers+KA%22">LaFavers KA</searchLink>; Department of Anatomy, Cell Biology and Physiology, Medicine.<br /><searchLink fieldCode="AU" term="%22Micanovic+R%22">Micanovic R</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Lazar+V%22">Lazar V</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Khan+S%22">Khan S</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Barwinska+D%22">Barwinska D</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Makino+S%22">Makino S</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Zollman+A%22">Zollman A</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Cheng+YH%22">Cheng YH</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Doud+EH%22">Doud EH</searchLink>; Department of Biochemistry and Molecular Biology.; Center for Proteome Analysis.<br /><searchLink fieldCode="AU" term="%22Mosley+AL%22">Mosley AL</searchLink>; Department of Biochemistry and Molecular Biology.; Center for Proteome Analysis.; Center for Computational Biology and Bioinformatics.<br /><searchLink fieldCode="AU" term="%22Repass+MJ%22">Repass MJ</searchLink>; Cellular Response Technologies Core, and.<br /><searchLink fieldCode="AU" term="%22Kamocka+MM%22">Kamocka MM</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Baride+A%22">Baride A</searchLink>; Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Phillips+CL%22">Phillips CL</searchLink>; Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Kelly+KJ%22">Kelly KJ</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.; Indianapolis Roudebush VA Medical Center, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Eadon+MT%22">Eadon MT</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Himmelfarb+J%22">Himmelfarb J</searchLink>; Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Kretzler+M%22">Kretzler M</searchLink>; Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Bacallao+RL%22">Bacallao RL</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Dagher+PC%22">Dagher PC</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.<br /><searchLink fieldCode="AU" term="%22Hato+T%22">Hato T</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.; Indianapolis Roudebush VA Medical Center, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22El-Achkar+TM%22">El-Achkar TM</searchLink>; Department of Medicine, Division of Nephrology and Hypertension.; Department of Anatomy, Cell Biology and Physiology, Medicine.; Indianapolis Roudebush VA Medical Center, Indianapolis, Indiana, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Apr 08; Vol. 135 (12). <i>Date of Electronic Publication: </i>2025 Apr 08 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1172/JCI183343
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        Text: English
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              Text: 2025 Apr 08
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